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Association details:
Biomarker:
GJA1 expression
Cancer:
Triple Negative Breast Cancer
Drug:
JQ-1
(
BET inhibitor
)
Direction:
Resistant
Evidence:
Evidence Level:
Resistant: C3 – Early Trials
Source:
ESMO 2019
Title:
IDENTIFICATION OF A STEMNESS-RELATED GENE PANEL ASSOCIATED WITH BET INHIBITION IN TRIPLE NEGATIVE BREAST CANCER
Published date:
09/30/2019
Excerpt:
Four of the identified stemness genes, GJA1, CD24, EPCAM, and SOX9, were found to be associated with worse patient outcome in TNBC.
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