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DRUG:

IMGN779

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Company:

AbbVie, Jazz

Drug class:

DNA replication inhibitor, CD33-targeted antibody-drug conjugate

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CD33 expression	Acute Myelogenous Leukemia	CD33 expression	Acute Myelogenous Leukemia	IMGN779 Sensitive: C3 – Early Trials IMGN779 Sensitive : C3	IMGN779 Sensitive: C3 – Early Trials IMGN779 Sensitive : C3
FLT3-ITD mutation	Acute Myelogenous Leukemia	FLT3-ITD mutation	Acute Myelogenous Leukemia	quizartinib + IMGN779 Sensitive: D – Preclinical quizartinib + IMGN779 Sensitive : D	quizartinib + IMGN779 Sensitive: D – Preclinical quizartinib + IMGN779 Sensitive : D
CD33 positive	Acute Myelogenous Leukemia	CD33 positive	Acute Myelogenous Leukemia	IMGN779 Sensitive: D – Preclinical IMGN779 Sensitive : D	IMGN779 Sensitive: D – Preclinical IMGN779 Sensitive : D