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DRUG:
Besponsa (inotuzumab ozogamicin)
i
Other names:
CMC-544 , WAY-207294, PF-5208773
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Associations
(28)
News
Trials
Company:
Pfizer, UCB
Drug class:
DNA replication inhibitor, CD22-targeted antibody-drug conjugate
Related drugs:
‹
gemtuzumab ozogamicin (24)
idarubicin (22)
bendamustine (12)
loncastuximab tesirine-lpyl (7)
trastuzumab duocarmazine (6)
MEDI7247 (6)
ABBV-321 (6)
rovalpituzumab tesirine (5)
SGN-CD19B (5)
SOT102 (5)
MGC018 (5)
IMGN632 (4)
IMGN779 (3)
ADCT-301 (3)
BYON3521 (2)
CS5001 (2)
IKS03 (2)
ITC-6102RO (2)
NBE-002 (2)
SGN-CD123A (2)
SGN-CD352A (2)
TR1801-ADC (2)
ADCT-601 (2)
SGN-CD33A (2)
ADCT-211 (1)
ADCT-212 (1)
ADCT-701 (1)
DHES0815A (1)
MEDI3726 (1)
SGN-CD70A (1)
SC-003 (1)
ADCT-502 (0)
MDX-1203 (0)
MEDI2228 (0)
nimorazole (0)
PF-06647263 (0)
SC-006 (0)
SC-007 (0)
SYD1875 (0)
ADCT-602 (0)
TRPH-222 (1)
OXS-1550 (0)
RG7593 (0)
gemtuzumab ozogamicin (24)
idarubicin (22)
bendamustine (12)
loncastuximab tesirine-lpyl (7)
trastuzumab duocarmazine (6)
MEDI7247 (6)
ABBV-321 (6)
rovalpituzumab tesirine (5)
SGN-CD19B (5)
SOT102 (5)
MGC018 (5)
IMGN632 (4)
IMGN779 (3)
ADCT-301 (3)
BYON3521 (2)
CS5001 (2)
IKS03 (2)
ITC-6102RO (2)
NBE-002 (2)
SGN-CD123A (2)
SGN-CD352A (2)
TR1801-ADC (2)
ADCT-601 (2)
SGN-CD33A (2)
ADCT-211 (1)
ADCT-212 (1)
ADCT-701 (1)
DHES0815A (1)
MEDI3726 (1)
SGN-CD70A (1)
SC-003 (1)
ADCT-502 (0)
MDX-1203 (0)
MEDI2228 (0)
nimorazole (0)
PF-06647263 (0)
SC-006 (0)
SC-007 (0)
SYD1875 (0)
ADCT-602 (0)
TRPH-222 (1)
OXS-1550 (0)
RG7593 (0)
›
Associations
(28)
News
Trials
VERI cancer hierarchy
Reset Filters
CD22 positive
B Acute Lymphoblastic Leukemia
CD22 positive
B Acute Lymphoblastic Leukemia
inotuzumab ozogamicin
Sensitive: A1 - Approval
inotuzumab ozogamicin
Sensitive
:
A1
inotuzumab ozogamicin
Sensitive: A1 - Approval
inotuzumab ozogamicin
Sensitive
:
A1
BCR-ABL1 fusion
B Acute Lymphoblastic Leukemia
BCR-ABL1 fusion
B Acute Lymphoblastic Leukemia
inotuzumab ozogamicin
Sensitive: A1 - Approval
inotuzumab ozogamicin
Sensitive
:
A1
inotuzumab ozogamicin
Sensitive: A1 - Approval
inotuzumab ozogamicin
Sensitive
:
A1
No biomarker
B Acute Lymphoblastic Leukemia
No biomarker
B Acute Lymphoblastic Leukemia
inotuzumab ozogamicin
Sensitive: A1 - Approval
inotuzumab ozogamicin
Sensitive
:
A1
inotuzumab ozogamicin
Sensitive: A1 - Approval
inotuzumab ozogamicin
Sensitive
:
A1
BCR-ABL1 fusion
Acute Lymphocytic Leukemia
BCR-ABL1 fusion
Acute Lymphocytic Leukemia
inotuzumab ozogamicin
Sensitive: A2 - Guideline
inotuzumab ozogamicin
Sensitive
:
A2
inotuzumab ozogamicin
Sensitive: A2 - Guideline
inotuzumab ozogamicin
Sensitive
:
A2
No biomarker
Acute Lymphocytic Leukemia
No biomarker
Acute Lymphocytic Leukemia
inotuzumab ozogamicin
Sensitive: A2 - Guideline
inotuzumab ozogamicin
Sensitive
:
A2
inotuzumab ozogamicin
Sensitive: A2 - Guideline
inotuzumab ozogamicin
Sensitive
:
A2
No biomarker
Acute Lymphocytic Leukemia
No biomarker
Acute Lymphocytic Leukemia
blinatumomab + inotuzumab ozogamicin
Sensitive: A2 - Guideline
blinatumomab + inotuzumab ozogamicin
Sensitive
:
A2
blinatumomab + inotuzumab ozogamicin
Sensitive: A2 - Guideline
blinatumomab + inotuzumab ozogamicin
Sensitive
:
A2
No biomarker
B Acute Lymphoblastic Leukemia
No biomarker
B Acute Lymphoblastic Leukemia
blinatumomab + inotuzumab ozogamicin
Sensitive: A2 - Guideline
blinatumomab + inotuzumab ozogamicin
Sensitive
:
A2
blinatumomab + inotuzumab ozogamicin
Sensitive: A2 - Guideline
blinatumomab + inotuzumab ozogamicin
Sensitive
:
A2
BCR-ABL1 fusion
Acute Lymphocytic Leukemia
BCR-ABL1 fusion
Acute Lymphocytic Leukemia
bosutinib + inotuzumab ozogamicin
Sensitive: C2 – Inclusion Criteria
bosutinib + inotuzumab ozogamicin
Sensitive
:
C2
bosutinib + inotuzumab ozogamicin
Sensitive: C2 – Inclusion Criteria
bosutinib + inotuzumab ozogamicin
Sensitive
:
C2
CD22 positive
B Acute Lymphoblastic Leukemia
CD22 positive
B Acute Lymphoblastic Leukemia
blinatumomab + inotuzumab ozogamicin
Sensitive: C2 – Inclusion Criteria
blinatumomab + inotuzumab ozogamicin
Sensitive
:
C2
blinatumomab + inotuzumab ozogamicin
Sensitive: C2 – Inclusion Criteria
blinatumomab + inotuzumab ozogamicin
Sensitive
:
C2
CD22 expression
B Acute Lymphoblastic Leukemia
CD22 expression
B Acute Lymphoblastic Leukemia
inotuzumab ozogamicin
Sensitive: C2 – Inclusion Criteria
inotuzumab ozogamicin
Sensitive
:
C2
inotuzumab ozogamicin
Sensitive: C2 – Inclusion Criteria
inotuzumab ozogamicin
Sensitive
:
C2
CD22 expression
B Acute Lymphoblastic Leukemia
CD22 expression
B Acute Lymphoblastic Leukemia
blinatumomab + inotuzumab ozogamicin
Sensitive: C2 – Inclusion Criteria
blinatumomab + inotuzumab ozogamicin
Sensitive
:
C2
blinatumomab + inotuzumab ozogamicin
Sensitive: C2 – Inclusion Criteria
blinatumomab + inotuzumab ozogamicin
Sensitive
:
C2
MLL rearrangement
Acute Lymphocytic Leukemia
MLL rearrangement
Acute Lymphocytic Leukemia
blinatumomab + inotuzumab ozogamicin
Resistant: C3 – Early Trials
blinatumomab + inotuzumab ozogamicin
Resistant
:
C3
blinatumomab + inotuzumab ozogamicin
Resistant: C3 – Early Trials
blinatumomab + inotuzumab ozogamicin
Resistant
:
C3
MLL rearrangement
Acute Lymphocytic Leukemia
MLL rearrangement
Acute Lymphocytic Leukemia
inotuzumab ozogamicin
Resistant: C3 – Early Trials
inotuzumab ozogamicin
Resistant
:
C3
inotuzumab ozogamicin
Resistant: C3 – Early Trials
inotuzumab ozogamicin
Resistant
:
C3
TP53 mutation
B Acute Lymphoblastic Leukemia
TP53 mutation
B Acute Lymphoblastic Leukemia
blinatumomab + inotuzumab ozogamicin
Resistant: C3 – Early Trials
blinatumomab + inotuzumab ozogamicin
Resistant
:
C3
blinatumomab + inotuzumab ozogamicin
Resistant: C3 – Early Trials
blinatumomab + inotuzumab ozogamicin
Resistant
:
C3
TP53 mutation + IKZF3 mutation
B Acute Lymphoblastic Leukemia
TP53 mutation + IKZF3 mutation
B Acute Lymphoblastic Leukemia
inotuzumab ozogamicin
Sensitive: C3 – Early Trials
inotuzumab ozogamicin
Sensitive
:
C3
inotuzumab ozogamicin
Sensitive: C3 – Early Trials
inotuzumab ozogamicin
Sensitive
:
C3
TP53 mutation + IKZF1 mutation
B Acute Lymphoblastic Leukemia
TP53 mutation + IKZF1 mutation
B Acute Lymphoblastic Leukemia
inotuzumab ozogamicin
Sensitive: C3 – Early Trials
inotuzumab ozogamicin
Sensitive
:
C3
inotuzumab ozogamicin
Sensitive: C3 – Early Trials
inotuzumab ozogamicin
Sensitive
:
C3
IKZF3 mutation
B Acute Lymphoblastic Leukemia
IKZF3 mutation
B Acute Lymphoblastic Leukemia
inotuzumab ozogamicin
Sensitive: C3 – Early Trials
inotuzumab ozogamicin
Sensitive
:
C3
inotuzumab ozogamicin
Sensitive: C3 – Early Trials
inotuzumab ozogamicin
Sensitive
:
C3
TP53 deletion
B Acute Lymphoblastic Leukemia
TP53 deletion
B Acute Lymphoblastic Leukemia
inotuzumab ozogamicin
Sensitive: C3 – Early Trials
inotuzumab ozogamicin
Sensitive
:
C3
inotuzumab ozogamicin
Sensitive: C3 – Early Trials
inotuzumab ozogamicin
Sensitive
:
C3
IKZF1 mutation
B Acute Lymphoblastic Leukemia
IKZF1 mutation
B Acute Lymphoblastic Leukemia
inotuzumab ozogamicin
Sensitive: C3 – Early Trials
inotuzumab ozogamicin
Sensitive
:
C3
inotuzumab ozogamicin
Sensitive: C3 – Early Trials
inotuzumab ozogamicin
Sensitive
:
C3
TP53 mutation
B Acute Lymphoblastic Leukemia
TP53 mutation
B Acute Lymphoblastic Leukemia
inotuzumab ozogamicin
Sensitive: C3 – Early Trials
inotuzumab ozogamicin
Sensitive
:
C3
inotuzumab ozogamicin
Sensitive: C3 – Early Trials
inotuzumab ozogamicin
Sensitive
:
C3
CD22 overexpression
Acute Lymphocytic Leukemia
CD22 overexpression
Acute Lymphocytic Leukemia
inotuzumab ozogamicin
Sensitive: C3 – Early Trials
inotuzumab ozogamicin
Sensitive
:
C3
inotuzumab ozogamicin
Sensitive: C3 – Early Trials
inotuzumab ozogamicin
Sensitive
:
C3
CD22 underexpression + BCL2 overexpression
Acute Lymphocytic Leukemia
CD22 underexpression + BCL2 overexpression
Acute Lymphocytic Leukemia
inotuzumab ozogamicin
Resistant: C3 – Early Trials
inotuzumab ozogamicin
Resistant
:
C3
inotuzumab ozogamicin
Resistant: C3 – Early Trials
inotuzumab ozogamicin
Resistant
:
C3
CRLF2 overexpression
B Acute Lymphoblastic Leukemia
CRLF2 overexpression
B Acute Lymphoblastic Leukemia
inotuzumab ozogamicin
Sensitive: C3 – Early Trials
inotuzumab ozogamicin
Sensitive
:
C3
inotuzumab ozogamicin
Sensitive: C3 – Early Trials
inotuzumab ozogamicin
Sensitive
:
C3
CRLF2 overexpression
B Acute Lymphoblastic Leukemia
CRLF2 overexpression
B Acute Lymphoblastic Leukemia
blinatumomab + inotuzumab ozogamicin
Sensitive: C3 – Early Trials
blinatumomab + inotuzumab ozogamicin
Sensitive
:
C3
blinatumomab + inotuzumab ozogamicin
Sensitive: C3 – Early Trials
blinatumomab + inotuzumab ozogamicin
Sensitive
:
C3
TP53 mutation
Diffuse Large B Cell Lymphoma
TP53 mutation
Diffuse Large B Cell Lymphoma
inotuzumab ozogamicin
Sensitive: C3 – Early Trials
inotuzumab ozogamicin
Sensitive
:
C3
inotuzumab ozogamicin
Sensitive: C3 – Early Trials
inotuzumab ozogamicin
Sensitive
:
C3
CD79B mutation
Diffuse Large B Cell Lymphoma
CD79B mutation
Diffuse Large B Cell Lymphoma
inotuzumab ozogamicin
Sensitive: C3 – Early Trials
inotuzumab ozogamicin
Sensitive
:
C3
inotuzumab ozogamicin
Sensitive: C3 – Early Trials
inotuzumab ozogamicin
Sensitive
:
C3
MYD88 mutation
Diffuse Large B Cell Lymphoma
MYD88 mutation
Diffuse Large B Cell Lymphoma
inotuzumab ozogamicin
Sensitive: C3 – Early Trials
inotuzumab ozogamicin
Sensitive
:
C3
inotuzumab ozogamicin
Sensitive: C3 – Early Trials
inotuzumab ozogamicin
Sensitive
:
C3
CD58 expression
B Acute Lymphoblastic Leukemia
CD58 expression
B Acute Lymphoblastic Leukemia
inotuzumab ozogamicin
Sensitive: C3 – Early Trials
inotuzumab ozogamicin
Sensitive
:
C3
inotuzumab ozogamicin
Sensitive: C3 – Early Trials
inotuzumab ozogamicin
Sensitive
:
C3
^
^
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