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DRUG:

pivekimab sunirine (PVEK)

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Company:

AbbVie

Drug class:

DNA replication inhibitor, CD123-targeted antibody-drug conjugate

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CD123 positive	Acute Myelogenous Leukemia	CD123 positive	Acute Myelogenous Leukemia	PVEK Sensitive: C2 – Inclusion Criteria PVEK Sensitive : C2	PVEK Sensitive: C2 – Inclusion Criteria PVEK Sensitive : C2
CD123 positive	Acute Myelogenous Leukemia	CD123 positive	Acute Myelogenous Leukemia	venetoclax + PVEK Sensitive: C2 – Inclusion Criteria venetoclax + PVEK Sensitive : C2	venetoclax + PVEK Sensitive: C2 – Inclusion Criteria venetoclax + PVEK Sensitive : C2
IL3RA positive	Acute Myelogenous Leukemia	IL3RA positive	Acute Myelogenous Leukemia	PVEK Sensitive: C2 – Inclusion Criteria PVEK Sensitive : C2	PVEK Sensitive: C2 – Inclusion Criteria PVEK Sensitive : C2
IL3RA expression	Childhood B Acute Lymphoblastic Leukemia	IL3RA expression	Childhood B Acute Lymphoblastic Leukemia	PVEK Sensitive: D – Preclinical PVEK Sensitive : D	PVEK Sensitive: D – Preclinical PVEK Sensitive : D