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BIOMARKER:
HRAS mutation
i
Other names:
HRAS, HRAS1, Harvey rat sarcoma viral oncogene homolog
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News alerts, weekly reports and conference planners
Entrez ID:
3265
Related biomarkers:
Expression
Mutation
Others
‹
FGF19 amplification + HRAS Q61R + TP53 672+2T>G (6)
FGF3 amplification + HRAS Q61R + TP53 672+2T>G (6)
FGF4 amplification + HRAS Q61R + TP53 672+2T>G (6)
HRAS Q61R + TP53 P278S + PD-L1 overexpression (1)
HRAS overexpression + PIK3CA amplification (1)
HRAS overexpression + PIK3CA mutation (1)
FGF19 amplification + HRAS Q61R + TP53 672+2T>G (6)
FGF3 amplification + HRAS Q61R + TP53 672+2T>G (6)
FGF4 amplification + HRAS Q61R + TP53 672+2T>G (6)
HRAS Q61R + TP53 P278S + PD-L1 overexpression (1)
HRAS overexpression + PIK3CA amplification (1)
HRAS overexpression + PIK3CA mutation (1)
›
Associations
News
Trials
VERI cancer hierarchy
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HRAS mutation
Squamous Cell Carcinoma of Head and Neck
HRAS mutation
Squamous Cell Carcinoma of Head and Neck
tipifarnib
Sensitive: B - Late Trials
tipifarnib
Sensitive
:
B
tipifarnib
Sensitive: B - Late Trials
tipifarnib
Sensitive
:
B
HRAS mutation
Urothelial Cancer
HRAS mutation
Urothelial Cancer
tipifarnib
Sensitive: C2 – Inclusion Criteria
tipifarnib
Sensitive
:
C2
tipifarnib
Sensitive: C2 – Inclusion Criteria
tipifarnib
Sensitive
:
C2
HRAS mutation
Salivary Gland Cancer
HRAS mutation
Salivary Gland Cancer
tipifarnib
Sensitive: C3 – Early Trials
tipifarnib
Sensitive
:
C3
tipifarnib
Sensitive: C3 – Early Trials
tipifarnib
Sensitive
:
C3
HRAS mutation
Squamous Cell Carcinoma of Head and Neck
HRAS mutation
Squamous Cell Carcinoma of Head and Neck
cetuximab
Resistant: C3 – Early Trials
cetuximab
Resistant
:
C3
cetuximab
Resistant: C3 – Early Trials
cetuximab
Resistant
:
C3
HRAS mutation
Solid Tumor
HRAS mutation
Solid Tumor
selumetinib
Resistant: C3 – Early Trials
selumetinib
Resistant
:
C3
selumetinib
Resistant: C3 – Early Trials
selumetinib
Resistant
:
C3
HRAS mutation
Melanoma
HRAS mutation
Melanoma
cobimetinib + RG6185
Sensitive: C3 – Early Trials
cobimetinib + RG6185
Sensitive
:
C3
cobimetinib + RG6185
Sensitive: C3 – Early Trials
cobimetinib + RG6185
Sensitive
:
C3
HRAS mutation
Rhabdomyosarcoma
HRAS mutation
Rhabdomyosarcoma
tipifarnib
Sensitive: D – Preclinical
tipifarnib
Sensitive
:
D
tipifarnib
Sensitive: D – Preclinical
tipifarnib
Sensitive
:
D
HRAS mutation
Endometrial Cancer
HRAS mutation
Endometrial Cancer
AZ 628
Sensitive: D – Preclinical
AZ 628
Sensitive
:
D
AZ 628
Sensitive: D – Preclinical
AZ 628
Sensitive
:
D
HRAS mutation
Endometrial Cancer
HRAS mutation
Endometrial Cancer
PD-0325901
Sensitive: D – Preclinical
PD-0325901
Sensitive
:
D
PD-0325901
Sensitive: D – Preclinical
PD-0325901
Sensitive
:
D
HRAS mutation
Bladder Cancer
HRAS mutation
Bladder Cancer
FL118
Sensitive: D – Preclinical
FL118
Sensitive
:
D
FL118
Sensitive: D – Preclinical
FL118
Sensitive
:
D
HRAS mutation
Rhabdomyosarcoma
HRAS mutation
Rhabdomyosarcoma
trametinib + tipifarnib
Sensitive: D – Preclinical
trametinib + tipifarnib
Sensitive
:
D
trametinib + tipifarnib
Sensitive: D – Preclinical
trametinib + tipifarnib
Sensitive
:
D
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