^
    BIOMARKER:

    HIF1A overexpression

    i
    Other names: HIF1A, bHLHe78, HIF-1alpha, HIF1, MOP1, PASD8, Hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
    Entrez ID:
    3091
    Related biomarkers:
    Expression
    Mutation
    Fusion
    HIF1A overexpression
    HER2 Negative Breast Cancer
    albumin-bound paclitaxel
    Sensitive: B - Late Trials
    HIF1A overexpression
    AML
    azacitidine
    Sensitive: C3 – Early Trials
    HIF1A overexpression
    MDS
    azacitidine
    Sensitive: C3 – Early Trials
    HIF1A overexpression
    SCCHN
    nimotuzumab
    Sensitive: C3 – Early Trials
    HIF1A overexpression
    SCCHN
    cisplatin
    Resistant: C3 – Early Trials
    HIF1A overexpression
    NSCLC
    EGFR inhibitor
    Resistant: D – Preclinical
    HIF1A overexpression
    Ovarian Cancer
    CB-839
    Sensitive: D – Preclinical
    HIF1A overexpression
    Ovarian Cancer
    olaparib + CB-839
    Sensitive: D – Preclinical
    HIF1A overexpression
    HCC
    sorafenib
    Resistant: D – Preclinical
    HIF1A overexpression
    CRC
    5-fluorouracil
    Resistant: D – Preclinical