^
Association details:
| Biomarker: | HIF1A overexpression |
|---|---|
| Cancer: | Non Small Cell Lung Cancer |
| Drug Class: | EGFR inhibitor |
| Direction: | Resistant |
Evidence:
Source:
Title:
High expression of hypoxia inducible factor 1a related with acquired resistant to EGFR tyrosine kinase inhibitors in NSCLC
Published date:
01/13/2021
Excerpt:
As the treatment going on, EGFR-TKIs sensitivity rate of low HIF-1α level group was much higher than that of high level group. The high expression of HIF-1α related with the acquired resistance of the first generation EGFR-TKIs...
DOI:
10.1038/s41598-020-79801-1
