Login
Evidence Feed
About
Diagnostics
New
Top genes
FAQ
Contact us
^
Login
Contact us
to learn more about
our Premium Content: News alerts, weekly reports and conference planners
BIOMARKER:
HER-2 expression
i
Other names:
ERBB2, CD340, HER-2, HER2, NEU, NGL, V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
Contact us
to learn more about our Premium Content:
News alerts, weekly reports and conference planners
Entrez ID:
2064
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
HER-2 amplification + RAS wild-type + BRAF wild-type (9)
HER-2 positive + HER-2 amplification (4)
RAS wild-type + HER-2 positive (4)
HER-2 amplification + KRAS G12D (3)
BRAF wild-type + HER-2 positive (2)
BRCA1 mutation + HER-2 negative (2)
BRCA2 mutation + HER-2 negative (2)
HER-2 S310F + HER-2 amplification (2)
HER-2 amplification + EGFR-ZNF880 fusion + EGFR E114K (2)
HER-2 amplification + HER-2 L755S (2)
HER-2 amplification + PD-L1 expression (2)
HER-2 amplification + RAS wild-type (2)
HER-2 expression + HER-2 D769H (2)
HER-2 expression + HER-2 L869R (2)
HER-2 expression + HER-2 amplification (2)
HER-2 expression + TMB-H (2)
RAS wild-type + BRAF wild-type + HER-2 positive (2)
TMB-H + HER-2 positive (2)
AR positive + HER-2 amplification (1)
BRCA1 mutation + HER-2 negative + ER positive + PGR positive (1)
CD74-NRG1 fusion + EGFR mutation + HER-2 mutation (1)
EGFR L858R + HER-2 amplification + PIK3CA overexpression (1)
EGFR T790M + HER-2 amplification (1)
EGFR exon 19 deletion + EGFR T790M + EGFR C797S + HER-2 amplification (1)
ER negative + HER-2 positive + PGR positive + PIK3CA mutation (1)
ER positive + HER-2 D769H + HER-2 V777L (1)
ERBB2 G778A + CCNE1 amplification (1)
ERBB3 mutation + HER-2 amplification (1)
ERBB4 mutation + HER-2 positive (1)
HER-2 amplification + AXL expression (1)
HER-2 amplification + BRAF wild-type (1)
HER-2 amplification + CCNE1 expression (1)
HER-2 amplification + EGFR mutation (1)
HER-2 amplification + ER positive + PGR negative (1)
HER-2 amplification + HER-2 R157W (1)
HER-2 amplification + HER-2 mutation (1)
HER-2 amplification + KRAS exon 2 wild-type (1)
HER-2 amplification + KRAS wild-type (1)
HER-2 elevation (1)
HER-2 elevation + TMB-H (1)
HER-2 elevation + TMB-L (1)
HER-2 exon 20 insertion + TMB-L + PD-L1 negative (1)
HER-2 mutation + HER-2 positive (1)
HER-2 mutation + TMB-H (1)
HER-2 overexpression + CCNE1 amplification (1)
HER-2 overexpression + HER-2 amplification (1)
HER-2 overexpression + KRAS G12C (1)
HER-2 overexpression + KRAS wild-type (1)
HER-2 overexpression + PTEN deletion (1)
HER-2 overexpression + RAS wild-type (1)
HER-2 positive + APC mutation (1)
HER-2 positive + GATA6 amplification (1)
HER-2 positive + MYC amplification (1)
HER-2 positive + TP53 mutation (1)
HER-2 underexpression + CCNE1 amplification (1)
HR positive + HER-2 amplification (1)
HR positive + HER-2 mutation (1)
KRAS G12D + HER-2 amplification + TMB-H (1)
KRAS mutation + HER-2 positive (1)
MSI-H + HER-2 amplification (1)
MSI-H/dMMR + HER-2 mutation (1)
NF1 mutation + HER-2 positive (1)
PD-L1 overexpression + HER-2 exon 20 insertion (1)
PIK3C3 mutation + HER-2 positive (1)
PIK3CA H1047R + HER-2 amplification (1)
PIK3CA mutation + HER-2 amplification (1)
PIK3CA mutation + HER-2 positive (1)
PIK3CA mutation + HR positive + HER-2 negative (1)
PIK3R1 mutation + HER-2 positive (1)
POLE E790Q + ERBB2 amplification + TMB-H (1)
RAS wild-type + HER-2 amplification (1)
RAS wild-type + HER-2 overexpression (1)
STAT6 deletion + HER-2 overexpression (1)
ER negative + HER-2 positive + PIK3CA H1047R (0)
ER positive + HER-2 negative + ER mutation (0)
HER-2 amplification + KRAS G12C (0)
HER-2 exon 20 mutation + HER-2 amplification (0)
HER-2 positive + FGFR1 amplification (0)
HER-2-H (0)
HR positive + HER-2 negative + TMB-L (0)
PIK3CA E453K + HER-2 positive (0)
PIK3CA E542K + HER-2 positive (0)
PIK3CA E542Q + HER-2 positive (0)
PIK3CA H1047L + HER-2 positive (0)
PIK3CA H1047R + HER-2 positive (0)
PIK3CA N345K + HER-2 positive (0)
PIK3CA amplification + HER-2 positive (0)
HER-2 amplification + RAS wild-type + BRAF wild-type (9)
HER-2 positive + HER-2 amplification (4)
RAS wild-type + HER-2 positive (4)
HER-2 amplification + KRAS G12D (3)
BRAF wild-type + HER-2 positive (2)
BRCA1 mutation + HER-2 negative (2)
BRCA2 mutation + HER-2 negative (2)
HER-2 S310F + HER-2 amplification (2)
HER-2 amplification + EGFR-ZNF880 fusion + EGFR E114K (2)
HER-2 amplification + HER-2 L755S (2)
HER-2 amplification + PD-L1 expression (2)
HER-2 amplification + RAS wild-type (2)
HER-2 expression + HER-2 D769H (2)
HER-2 expression + HER-2 L869R (2)
HER-2 expression + HER-2 amplification (2)
HER-2 expression + TMB-H (2)
RAS wild-type + BRAF wild-type + HER-2 positive (2)
TMB-H + HER-2 positive (2)
AR positive + HER-2 amplification (1)
BRCA1 mutation + HER-2 negative + ER positive + PGR positive (1)
CD74-NRG1 fusion + EGFR mutation + HER-2 mutation (1)
EGFR L858R + HER-2 amplification + PIK3CA overexpression (1)
EGFR T790M + HER-2 amplification (1)
EGFR exon 19 deletion + EGFR T790M + EGFR C797S + HER-2 amplification (1)
ER negative + HER-2 positive + PGR positive + PIK3CA mutation (1)
ER positive + HER-2 D769H + HER-2 V777L (1)
ERBB2 G778A + CCNE1 amplification (1)
ERBB3 mutation + HER-2 amplification (1)
ERBB4 mutation + HER-2 positive (1)
HER-2 amplification + AXL expression (1)
HER-2 amplification + BRAF wild-type (1)
HER-2 amplification + CCNE1 expression (1)
HER-2 amplification + EGFR mutation (1)
HER-2 amplification + ER positive + PGR negative (1)
HER-2 amplification + HER-2 R157W (1)
HER-2 amplification + HER-2 mutation (1)
HER-2 amplification + KRAS exon 2 wild-type (1)
HER-2 amplification + KRAS wild-type (1)
HER-2 elevation (1)
HER-2 elevation + TMB-H (1)
HER-2 elevation + TMB-L (1)
HER-2 exon 20 insertion + TMB-L + PD-L1 negative (1)
HER-2 mutation + HER-2 positive (1)
HER-2 mutation + TMB-H (1)
HER-2 overexpression + CCNE1 amplification (1)
HER-2 overexpression + HER-2 amplification (1)
HER-2 overexpression + KRAS G12C (1)
HER-2 overexpression + KRAS wild-type (1)
HER-2 overexpression + PTEN deletion (1)
HER-2 overexpression + RAS wild-type (1)
HER-2 positive + APC mutation (1)
HER-2 positive + GATA6 amplification (1)
HER-2 positive + MYC amplification (1)
HER-2 positive + TP53 mutation (1)
HER-2 underexpression + CCNE1 amplification (1)
HR positive + HER-2 amplification (1)
HR positive + HER-2 mutation (1)
KRAS G12D + HER-2 amplification + TMB-H (1)
KRAS mutation + HER-2 positive (1)
MSI-H + HER-2 amplification (1)
MSI-H/dMMR + HER-2 mutation (1)
NF1 mutation + HER-2 positive (1)
PD-L1 overexpression + HER-2 exon 20 insertion (1)
PIK3C3 mutation + HER-2 positive (1)
PIK3CA H1047R + HER-2 amplification (1)
PIK3CA mutation + HER-2 amplification (1)
PIK3CA mutation + HER-2 positive (1)
PIK3CA mutation + HR positive + HER-2 negative (1)
PIK3R1 mutation + HER-2 positive (1)
POLE E790Q + ERBB2 amplification + TMB-H (1)
RAS wild-type + HER-2 amplification (1)
RAS wild-type + HER-2 overexpression (1)
STAT6 deletion + HER-2 overexpression (1)
ER negative + HER-2 positive + PIK3CA H1047R (0)
ER positive + HER-2 negative + ER mutation (0)
HER-2 amplification + KRAS G12C (0)
HER-2 exon 20 mutation + HER-2 amplification (0)
HER-2 positive + FGFR1 amplification (0)
HER-2-H (0)
HR positive + HER-2 negative + TMB-L (0)
PIK3CA E453K + HER-2 positive (0)
PIK3CA E542K + HER-2 positive (0)
PIK3CA E542Q + HER-2 positive (0)
PIK3CA H1047L + HER-2 positive (0)
PIK3CA H1047R + HER-2 positive (0)
PIK3CA N345K + HER-2 positive (0)
PIK3CA amplification + HER-2 positive (0)
›
Related tests:
MammaTyper® Kit (1)
CercaTest™ ERBB2 Assay
MammaTyper® Kit (1)
CercaTest™ ERBB2 Assay
Associations
News
Trials
VERI cancer hierarchy
Reset Filters
HER-2 expression
Solid Tumor
HER-2 expression
Solid Tumor
fam-trastuzumab deruxtecan-nxki
Sensitive: A1 - Approval
fam-trastuzumab deruxtecan-nxki
Sensitive
:
A1
fam-trastuzumab deruxtecan-nxki
Sensitive: A1 - Approval
fam-trastuzumab deruxtecan-nxki
Sensitive
:
A1
HER-2 expression
Endometrial Adenocarcinoma
HER-2 expression
Endometrial Adenocarcinoma
trastuzumab
Sensitive: A2 - Guideline
trastuzumab
Sensitive
:
A2
trastuzumab
Sensitive: A2 - Guideline
trastuzumab
Sensitive
:
A2
HER-2 expression
Breast Cancer
HER-2 expression
Breast Cancer
JNJ-0683
Sensitive: B - Late Trials
JNJ-0683
Sensitive
:
B
JNJ-0683
Sensitive: B - Late Trials
JNJ-0683
Sensitive
:
B
HER-2 expression
Biliary Tract Cancer
HER-2 expression
Biliary Tract Cancer
ZW25
Sensitive: B - Late Trials
ZW25
Sensitive
:
B
ZW25
Sensitive: B - Late Trials
ZW25
Sensitive
:
B
HER-2 expression
Cholangiocarcinoma
HER-2 expression
Cholangiocarcinoma
trastuzumab + lapatinib
Sensitive: B - Late Trials
trastuzumab + lapatinib
Sensitive
:
B
trastuzumab + lapatinib
Sensitive: B - Late Trials
trastuzumab + lapatinib
Sensitive
:
B
HER-2 expression
Colorectal Cancer
HER-2 expression
Colorectal Cancer
fam-trastuzumab deruxtecan-nxki
Sensitive: B - Late Trials
fam-trastuzumab deruxtecan-nxki
Sensitive
:
B
fam-trastuzumab deruxtecan-nxki
Sensitive: B - Late Trials
fam-trastuzumab deruxtecan-nxki
Sensitive
:
B
HER-2 expression
HER2 Positive Breast Cancer
HER-2 expression
HER2 Positive Breast Cancer
pertuzumab + ado-trastuzumab emtansine
Sensitive: B - Late Trials
pertuzumab + ado-trastuzumab emtansine
Sensitive
:
B
pertuzumab + ado-trastuzumab emtansine
Sensitive: B - Late Trials
pertuzumab + ado-trastuzumab emtansine
Sensitive
:
B
HER-2 expression
Endometrial Cancer
HER-2 expression
Endometrial Cancer
BNT323
Sensitive: B - Late Trials
BNT323
Sensitive
:
B
BNT323
Sensitive: B - Late Trials
BNT323
Sensitive
:
B
HER-2 expression
Endometrial Cancer
HER-2 expression
Endometrial Cancer
fam-trastuzumab deruxtecan-nxki
Sensitive: C1 - Off-label
fam-trastuzumab deruxtecan-nxki
Sensitive
:
C1
fam-trastuzumab deruxtecan-nxki
Sensitive: C1 - Off-label
fam-trastuzumab deruxtecan-nxki
Sensitive
:
C1
HER-2 expression
Gastroesophageal Junction Adenocarcinoma
HER-2 expression
Gastroesophageal Junction Adenocarcinoma
fam-trastuzumab deruxtecan-nxki
Sensitive: C1 - Off-label
fam-trastuzumab deruxtecan-nxki
Sensitive
:
C1
fam-trastuzumab deruxtecan-nxki
Sensitive: C1 - Off-label
fam-trastuzumab deruxtecan-nxki
Sensitive
:
C1
HER-2 expression
Salivary Gland Cancer
HER-2 expression
Salivary Gland Cancer
fam-trastuzumab deruxtecan-nxki
Sensitive: C1 - Off-label
fam-trastuzumab deruxtecan-nxki
Sensitive
:
C1
fam-trastuzumab deruxtecan-nxki
Sensitive: C1 - Off-label
fam-trastuzumab deruxtecan-nxki
Sensitive
:
C1
HER-2 expression
Uterine Cancer
HER-2 expression
Uterine Cancer
fam-trastuzumab deruxtecan-nxki
Sensitive: C1 - Off-label
fam-trastuzumab deruxtecan-nxki
Sensitive
:
C1
fam-trastuzumab deruxtecan-nxki
Sensitive: C1 - Off-label
fam-trastuzumab deruxtecan-nxki
Sensitive
:
C1
HER-2 expression
Non Small Cell Lung Cancer
HER-2 expression
Non Small Cell Lung Cancer
fam-trastuzumab deruxtecan-nxki
Sensitive: C1 - Off-label
fam-trastuzumab deruxtecan-nxki
Sensitive
:
C1
fam-trastuzumab deruxtecan-nxki
Sensitive: C1 - Off-label
fam-trastuzumab deruxtecan-nxki
Sensitive
:
C1
HER-2 expression
Breast Cancer
HER-2 expression
Breast Cancer
fam-trastuzumab deruxtecan-nxki
Sensitive: C1 - Off-label
fam-trastuzumab deruxtecan-nxki
Sensitive
:
C1
fam-trastuzumab deruxtecan-nxki
Sensitive: C1 - Off-label
fam-trastuzumab deruxtecan-nxki
Sensitive
:
C1
HER-2 expression
Biliary Tract Cancer
HER-2 expression
Biliary Tract Cancer
fam-trastuzumab deruxtecan-nxki
Sensitive: C1 - Off-label
fam-trastuzumab deruxtecan-nxki
Sensitive
:
C1
fam-trastuzumab deruxtecan-nxki
Sensitive: C1 - Off-label
fam-trastuzumab deruxtecan-nxki
Sensitive
:
C1
HER-2 expression
Pancreatic Cancer
HER-2 expression
Pancreatic Cancer
fam-trastuzumab deruxtecan-nxki
Sensitive: C1 - Off-label
fam-trastuzumab deruxtecan-nxki
Sensitive
:
C1
fam-trastuzumab deruxtecan-nxki
Sensitive: C1 - Off-label
fam-trastuzumab deruxtecan-nxki
Sensitive
:
C1
HER-2 expression
Bladder Cancer
HER-2 expression
Bladder Cancer
fam-trastuzumab deruxtecan-nxki
Sensitive: C1 - Off-label
fam-trastuzumab deruxtecan-nxki
Sensitive
:
C1
fam-trastuzumab deruxtecan-nxki
Sensitive: C1 - Off-label
fam-trastuzumab deruxtecan-nxki
Sensitive
:
C1
HER-2 expression
Ovarian Cancer
HER-2 expression
Ovarian Cancer
fam-trastuzumab deruxtecan-nxki
Sensitive: C1 - Off-label
fam-trastuzumab deruxtecan-nxki
Sensitive
:
C1
fam-trastuzumab deruxtecan-nxki
Sensitive: C1 - Off-label
fam-trastuzumab deruxtecan-nxki
Sensitive
:
C1
HER-2 expression
Cervical Cancer
HER-2 expression
Cervical Cancer
fam-trastuzumab deruxtecan-nxki
Sensitive: C1 - Off-label
fam-trastuzumab deruxtecan-nxki
Sensitive
:
C1
fam-trastuzumab deruxtecan-nxki
Sensitive: C1 - Off-label
fam-trastuzumab deruxtecan-nxki
Sensitive
:
C1
HER-2 expression
HER2 Positive Breast Cancer
HER-2 expression
HER2 Positive Breast Cancer
trastuzumab + pertuzumab
Sensitive: C2 – Inclusion Criteria
trastuzumab + pertuzumab
Sensitive
:
C2
trastuzumab + pertuzumab
Sensitive: C2 – Inclusion Criteria
trastuzumab + pertuzumab
Sensitive
:
C2
HER-2 expression
Gastric Cancer
HER-2 expression
Gastric Cancer
trastuzumab
Sensitive: C2 – Inclusion Criteria
trastuzumab
Sensitive
:
C2
trastuzumab
Sensitive: C2 – Inclusion Criteria
trastuzumab
Sensitive
:
C2
HER-2 expression
HER2 Positive Breast Cancer
HER-2 expression
HER2 Positive Breast Cancer
trastuzumab
Sensitive: C2 – Inclusion Criteria
trastuzumab
Sensitive
:
C2
trastuzumab
Sensitive: C2 – Inclusion Criteria
trastuzumab
Sensitive
:
C2
HER-2 expression
Gastric Cancer
HER-2 expression
Gastric Cancer
A166
Sensitive: C2 – Inclusion Criteria
A166
Sensitive
:
C2
A166
Sensitive: C2 – Inclusion Criteria
A166
Sensitive
:
C2
HER-2 expression
Breast Cancer
HER-2 expression
Breast Cancer
lapatinib
Sensitive: C2 – Inclusion Criteria
lapatinib
Sensitive
:
C2
lapatinib
Sensitive: C2 – Inclusion Criteria
lapatinib
Sensitive
:
C2
HER-2 expression
Colorectal Cancer
HER-2 expression
Colorectal Cancer
A166
Sensitive: C2 – Inclusion Criteria
A166
Sensitive
:
C2
A166
Sensitive: C2 – Inclusion Criteria
A166
Sensitive
:
C2
HER-2 expression
HER2 Positive Breast Cancer
HER-2 expression
HER2 Positive Breast Cancer
A166
Sensitive: C2 – Inclusion Criteria
A166
Sensitive
:
C2
A166
Sensitive: C2 – Inclusion Criteria
A166
Sensitive
:
C2
HER-2 expression
HER2 Positive Breast Cancer
HER-2 expression
HER2 Positive Breast Cancer
avelumab
Sensitive: C2 – Inclusion Criteria
avelumab
Sensitive
:
C2
avelumab
Sensitive: C2 – Inclusion Criteria
avelumab
Sensitive
:
C2
HER-2 expression
Colorectal Cancer
HER-2 expression
Colorectal Cancer
cetuximab
Sensitive: C2 – Inclusion Criteria
cetuximab
Sensitive
:
C2
cetuximab
Sensitive: C2 – Inclusion Criteria
cetuximab
Sensitive
:
C2
HER-2 expression
Solid Tumor
HER-2 expression
Solid Tumor
SBT6050
Sensitive: C2 – Inclusion Criteria
SBT6050
Sensitive
:
C2
SBT6050
Sensitive: C2 – Inclusion Criteria
SBT6050
Sensitive
:
C2
HER-2 expression
Gastric Cancer
HER-2 expression
Gastric Cancer
AST-301
Sensitive: C2 – Inclusion Criteria
AST-301
Sensitive
:
C2
AST-301
Sensitive: C2 – Inclusion Criteria
AST-301
Sensitive
:
C2
HER-2 expression
Gastric Cancer
HER-2 expression
Gastric Cancer
disitamab vedotin
Sensitive: C2 – Inclusion Criteria
disitamab vedotin
Sensitive
:
C2
disitamab vedotin
Sensitive: C2 – Inclusion Criteria
disitamab vedotin
Sensitive
:
C2
HER-2 expression
Gastroesophageal Junction Adenocarcinoma
HER-2 expression
Gastroesophageal Junction Adenocarcinoma
KN026
Sensitive: C2 – Inclusion Criteria
KN026
Sensitive
:
C2
KN026
Sensitive: C2 – Inclusion Criteria
KN026
Sensitive
:
C2
^
^
Full access to predictive biomarker details and heatmap analytics are available with a VERI Account.
Sign up for FREE
Already have an account?
Login
Full access to predictive biomarker details and heatmap analytics are available with a VERI Account.
Sign up for FREE
Already have an account?
Login