HER-2 expression	Solid Tumor	HER-2 expression	Solid Tumor	fam-trastuzumab deruxtecan-nxki Sensitive: A1 - Approval fam-trastuzumab deruxtecan-nxki Sensitive : A1	fam-trastuzumab deruxtecan-nxki Sensitive: A1 - Approval fam-trastuzumab deruxtecan-nxki Sensitive : A1
HER-2 expression	Endometrial Adenocarcinoma	HER-2 expression	Endometrial Adenocarcinoma	trastuzumab Sensitive: A2 - Guideline trastuzumab Sensitive : A2	trastuzumab Sensitive: A2 - Guideline trastuzumab Sensitive : A2
HER-2 expression	Breast Cancer	HER-2 expression	Breast Cancer	JNJ-0683 Sensitive: B - Late Trials JNJ-0683 Sensitive : B	JNJ-0683 Sensitive: B - Late Trials JNJ-0683 Sensitive : B
HER-2 expression	Biliary Tract Cancer	HER-2 expression	Biliary Tract Cancer	ZW25 Sensitive: B - Late Trials ZW25 Sensitive : B	ZW25 Sensitive: B - Late Trials ZW25 Sensitive : B
HER-2 expression	Cholangiocarcinoma	HER-2 expression	Cholangiocarcinoma	trastuzumab + lapatinib Sensitive: B - Late Trials trastuzumab + lapatinib Sensitive : B	trastuzumab + lapatinib Sensitive: B - Late Trials trastuzumab + lapatinib Sensitive : B
HER-2 expression	Colorectal Cancer	HER-2 expression	Colorectal Cancer	fam-trastuzumab deruxtecan-nxki Sensitive: B - Late Trials fam-trastuzumab deruxtecan-nxki Sensitive : B	fam-trastuzumab deruxtecan-nxki Sensitive: B - Late Trials fam-trastuzumab deruxtecan-nxki Sensitive : B
HER-2 expression	HER2 Positive Breast Cancer	HER-2 expression	HER2 Positive Breast Cancer	pertuzumab + ado-trastuzumab emtansine Sensitive: B - Late Trials pertuzumab + ado-trastuzumab emtansine Sensitive : B	pertuzumab + ado-trastuzumab emtansine Sensitive: B - Late Trials pertuzumab + ado-trastuzumab emtansine Sensitive : B
HER-2 expression	Endometrial Cancer	HER-2 expression	Endometrial Cancer	BNT323 Sensitive: B - Late Trials BNT323 Sensitive : B	BNT323 Sensitive: B - Late Trials BNT323 Sensitive : B
HER-2 expression	Endometrial Cancer	HER-2 expression	Endometrial Cancer	fam-trastuzumab deruxtecan-nxki Sensitive: C1 - Off-label fam-trastuzumab deruxtecan-nxki Sensitive : C1	fam-trastuzumab deruxtecan-nxki Sensitive: C1 - Off-label fam-trastuzumab deruxtecan-nxki Sensitive : C1
HER-2 expression	Gastroesophageal Junction Adenocarcinoma	HER-2 expression	Gastroesophageal Junction Adenocarcinoma	fam-trastuzumab deruxtecan-nxki Sensitive: C1 - Off-label fam-trastuzumab deruxtecan-nxki Sensitive : C1	fam-trastuzumab deruxtecan-nxki Sensitive: C1 - Off-label fam-trastuzumab deruxtecan-nxki Sensitive : C1
HER-2 expression	Salivary Gland Cancer	HER-2 expression	Salivary Gland Cancer	fam-trastuzumab deruxtecan-nxki Sensitive: C1 - Off-label fam-trastuzumab deruxtecan-nxki Sensitive : C1	fam-trastuzumab deruxtecan-nxki Sensitive: C1 - Off-label fam-trastuzumab deruxtecan-nxki Sensitive : C1
HER-2 expression	Uterine Cancer	HER-2 expression	Uterine Cancer	fam-trastuzumab deruxtecan-nxki Sensitive: C1 - Off-label fam-trastuzumab deruxtecan-nxki Sensitive : C1	fam-trastuzumab deruxtecan-nxki Sensitive: C1 - Off-label fam-trastuzumab deruxtecan-nxki Sensitive : C1
HER-2 expression	Non Small Cell Lung Cancer	HER-2 expression	Non Small Cell Lung Cancer	fam-trastuzumab deruxtecan-nxki Sensitive: C1 - Off-label fam-trastuzumab deruxtecan-nxki Sensitive : C1	fam-trastuzumab deruxtecan-nxki Sensitive: C1 - Off-label fam-trastuzumab deruxtecan-nxki Sensitive : C1
HER-2 expression	Breast Cancer	HER-2 expression	Breast Cancer	fam-trastuzumab deruxtecan-nxki Sensitive: C1 - Off-label fam-trastuzumab deruxtecan-nxki Sensitive : C1	fam-trastuzumab deruxtecan-nxki Sensitive: C1 - Off-label fam-trastuzumab deruxtecan-nxki Sensitive : C1
HER-2 expression	Biliary Tract Cancer	HER-2 expression	Biliary Tract Cancer	fam-trastuzumab deruxtecan-nxki Sensitive: C1 - Off-label fam-trastuzumab deruxtecan-nxki Sensitive : C1	fam-trastuzumab deruxtecan-nxki Sensitive: C1 - Off-label fam-trastuzumab deruxtecan-nxki Sensitive : C1
HER-2 expression	Pancreatic Cancer	HER-2 expression	Pancreatic Cancer	fam-trastuzumab deruxtecan-nxki Sensitive: C1 - Off-label fam-trastuzumab deruxtecan-nxki Sensitive : C1	fam-trastuzumab deruxtecan-nxki Sensitive: C1 - Off-label fam-trastuzumab deruxtecan-nxki Sensitive : C1
HER-2 expression	Bladder Cancer	HER-2 expression	Bladder Cancer	fam-trastuzumab deruxtecan-nxki Sensitive: C1 - Off-label fam-trastuzumab deruxtecan-nxki Sensitive : C1	fam-trastuzumab deruxtecan-nxki Sensitive: C1 - Off-label fam-trastuzumab deruxtecan-nxki Sensitive : C1
HER-2 expression	Ovarian Cancer	HER-2 expression	Ovarian Cancer	fam-trastuzumab deruxtecan-nxki Sensitive: C1 - Off-label fam-trastuzumab deruxtecan-nxki Sensitive : C1	fam-trastuzumab deruxtecan-nxki Sensitive: C1 - Off-label fam-trastuzumab deruxtecan-nxki Sensitive : C1
HER-2 expression	Cervical Cancer	HER-2 expression	Cervical Cancer	fam-trastuzumab deruxtecan-nxki Sensitive: C1 - Off-label fam-trastuzumab deruxtecan-nxki Sensitive : C1	fam-trastuzumab deruxtecan-nxki Sensitive: C1 - Off-label fam-trastuzumab deruxtecan-nxki Sensitive : C1
HER-2 expression	HER2 Positive Breast Cancer	HER-2 expression	HER2 Positive Breast Cancer	trastuzumab + pertuzumab Sensitive: C2 – Inclusion Criteria trastuzumab + pertuzumab Sensitive : C2	trastuzumab + pertuzumab Sensitive: C2 – Inclusion Criteria trastuzumab + pertuzumab Sensitive : C2
HER-2 expression	Gastric Cancer	HER-2 expression	Gastric Cancer	trastuzumab Sensitive: C2 – Inclusion Criteria trastuzumab Sensitive : C2	trastuzumab Sensitive: C2 – Inclusion Criteria trastuzumab Sensitive : C2
HER-2 expression	HER2 Positive Breast Cancer	HER-2 expression	HER2 Positive Breast Cancer	trastuzumab Sensitive: C2 – Inclusion Criteria trastuzumab Sensitive : C2	trastuzumab Sensitive: C2 – Inclusion Criteria trastuzumab Sensitive : C2
HER-2 expression	Gastric Cancer	HER-2 expression	Gastric Cancer	A166 Sensitive: C2 – Inclusion Criteria A166 Sensitive : C2	A166 Sensitive: C2 – Inclusion Criteria A166 Sensitive : C2
HER-2 expression	Breast Cancer	HER-2 expression	Breast Cancer	lapatinib Sensitive: C2 – Inclusion Criteria lapatinib Sensitive : C2	lapatinib Sensitive: C2 – Inclusion Criteria lapatinib Sensitive : C2
HER-2 expression	Colorectal Cancer	HER-2 expression	Colorectal Cancer	A166 Sensitive: C2 – Inclusion Criteria A166 Sensitive : C2	A166 Sensitive: C2 – Inclusion Criteria A166 Sensitive : C2
HER-2 expression	HER2 Positive Breast Cancer	HER-2 expression	HER2 Positive Breast Cancer	A166 Sensitive: C2 – Inclusion Criteria A166 Sensitive : C2	A166 Sensitive: C2 – Inclusion Criteria A166 Sensitive : C2
HER-2 expression	HER2 Positive Breast Cancer	HER-2 expression	HER2 Positive Breast Cancer	avelumab Sensitive: C2 – Inclusion Criteria avelumab Sensitive : C2	avelumab Sensitive: C2 – Inclusion Criteria avelumab Sensitive : C2
HER-2 expression	Colorectal Cancer	HER-2 expression	Colorectal Cancer	cetuximab Sensitive: C2 – Inclusion Criteria cetuximab Sensitive : C2	cetuximab Sensitive: C2 – Inclusion Criteria cetuximab Sensitive : C2
HER-2 expression	Solid Tumor	HER-2 expression	Solid Tumor	SBT6050 Sensitive: C2 – Inclusion Criteria SBT6050 Sensitive : C2	SBT6050 Sensitive: C2 – Inclusion Criteria SBT6050 Sensitive : C2
HER-2 expression	Gastric Cancer	HER-2 expression	Gastric Cancer	AST-301 Sensitive: C2 – Inclusion Criteria AST-301 Sensitive : C2	AST-301 Sensitive: C2 – Inclusion Criteria AST-301 Sensitive : C2
HER-2 expression	Gastric Cancer	HER-2 expression	Gastric Cancer	disitamab vedotin Sensitive: C2 – Inclusion Criteria disitamab vedotin Sensitive : C2	disitamab vedotin Sensitive: C2 – Inclusion Criteria disitamab vedotin Sensitive : C2
HER-2 expression	Gastroesophageal Junction Adenocarcinoma	HER-2 expression	Gastroesophageal Junction Adenocarcinoma	KN026 Sensitive: C2 – Inclusion Criteria KN026 Sensitive : C2	KN026 Sensitive: C2 – Inclusion Criteria KN026 Sensitive : C2

HER-2 expression

Associations