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BIOMARKER:
HER-2 expression
i
Other names:
ERBB2, CD340, HER-2, HER2, NEU, NGL, V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
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Entrez ID:
2064
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
HER-2 positive (332)
HER-2 overexpression (132)
HER-2 negative (120)
HER-2 underexpression (38)
HER-2 negative + PD-L1 expression (12)
HR positive + HER-2 negative (5)
HER-2 positive + PD-L1 expression (3)
CD47 positive + HER-2 positive (2)
CLDN18.2 expression + HER-2 negative (2)
CLDN18.2 positive + HER-2 negative (2)
EGFR overexpression + HER-2 overexpression (2)
ER positive + HER-2 negative (2)
FGFR2b overexpression + HER-2 negative (2)
HR positive + HER-2 underexpression (2)
PD-L1 expression + HER-2 overexpression (2)
CEACAM6 positive + HER-2 positive (1)
EGFR expression + HER-2 expression (1)
ER negative + HER-2 negative (1)
ER positive + PGR negative + HER-2 negative (1)
HER-2 positive + CAV1 overexpression (1)
HER-2 underexpression + ER underexpression (1)
HR positive + HER-2 positive (1)
MET expression + HER-2 expression (1)
MET overexpression + HER-2 overexpression (1)
TPBG underexpression + HER-2 overexpression (1)
TROP2 expression + HER-2 underexpression (1)
ER negative + HER-2 positive (0)
ER positive + HER-2 positive (0)
ER positive + PGR positive + HER-2 positive (0)
HER-2 amplification + HR-positive (0)
HER-2 negative + AR positive + ER positive (0)
HER-2 negative + CLDN18.2 positive (0)
HER-2 negative + ER positive (0)
HER-2 negative + FGFR2b overexpression (0)
HER-2 negative + HR negative (0)
HER-2 negative + HR negative + PD-L1 expression (0)
HER-2 negative + PGR positive (0)
HER-2 overexpression + HR negative (0)
HER-2 overexpression + HR positive (0)
HER-2 positive + HER-2 overexpression (0)
HER-2 positive + HR negative (0)
HER-2 positive + RAS wild-type (0)
HR negative + HER-2 positive (0)
PD-L1 expression + HER-2 expression (0)
PGR positive + HER-2 positive (0)
HER-2 positive (332)
HER-2 overexpression (132)
HER-2 negative (120)
HER-2 underexpression (38)
HER-2 negative + PD-L1 expression (12)
HR positive + HER-2 negative (5)
HER-2 positive + PD-L1 expression (3)
CD47 positive + HER-2 positive (2)
CLDN18.2 expression + HER-2 negative (2)
CLDN18.2 positive + HER-2 negative (2)
EGFR overexpression + HER-2 overexpression (2)
ER positive + HER-2 negative (2)
FGFR2b overexpression + HER-2 negative (2)
HR positive + HER-2 underexpression (2)
PD-L1 expression + HER-2 overexpression (2)
CEACAM6 positive + HER-2 positive (1)
EGFR expression + HER-2 expression (1)
ER negative + HER-2 negative (1)
ER positive + PGR negative + HER-2 negative (1)
HER-2 positive + CAV1 overexpression (1)
HER-2 underexpression + ER underexpression (1)
HR positive + HER-2 positive (1)
MET expression + HER-2 expression (1)
MET overexpression + HER-2 overexpression (1)
TPBG underexpression + HER-2 overexpression (1)
TROP2 expression + HER-2 underexpression (1)
ER negative + HER-2 positive (0)
ER positive + HER-2 positive (0)
ER positive + PGR positive + HER-2 positive (0)
HER-2 amplification + HR-positive (0)
HER-2 negative + AR positive + ER positive (0)
HER-2 negative + CLDN18.2 positive (0)
HER-2 negative + ER positive (0)
HER-2 negative + FGFR2b overexpression (0)
HER-2 negative + HR negative (0)
HER-2 negative + HR negative + PD-L1 expression (0)
HER-2 negative + PGR positive (0)
HER-2 overexpression + HR negative (0)
HER-2 overexpression + HR positive (0)
HER-2 positive + HER-2 overexpression (0)
HER-2 positive + HR negative (0)
HER-2 positive + RAS wild-type (0)
HR negative + HER-2 positive (0)
PD-L1 expression + HER-2 expression (0)
PGR positive + HER-2 positive (0)
›
Related tests:
MammaTyper® Kit (1)
CercaTest™ ERBB2 Assay
MammaTyper® Kit (1)
CercaTest™ ERBB2 Assay
Associations
News
Trials
VERI cancer hierarchy
Reset Filters
HER-2 expression
Solid Tumor
HER-2 expression
Solid Tumor
fam-trastuzumab deruxtecan-nxki
Sensitive: A1 - Approval
fam-trastuzumab deruxtecan-nxki
Sensitive
:
A1
fam-trastuzumab deruxtecan-nxki
Sensitive: A1 - Approval
fam-trastuzumab deruxtecan-nxki
Sensitive
:
A1
HER-2 expression
Endometrial Adenocarcinoma
HER-2 expression
Endometrial Adenocarcinoma
trastuzumab
Sensitive: A2 - Guideline
trastuzumab
Sensitive
:
A2
trastuzumab
Sensitive: A2 - Guideline
trastuzumab
Sensitive
:
A2
HER-2 expression
Breast Cancer
HER-2 expression
Breast Cancer
JNJ-0683
Sensitive: B - Late Trials
JNJ-0683
Sensitive
:
B
JNJ-0683
Sensitive: B - Late Trials
JNJ-0683
Sensitive
:
B
HER-2 expression
Biliary Tract Cancer
HER-2 expression
Biliary Tract Cancer
ZW25
Sensitive: B - Late Trials
ZW25
Sensitive
:
B
ZW25
Sensitive: B - Late Trials
ZW25
Sensitive
:
B
HER-2 expression
Cholangiocarcinoma
HER-2 expression
Cholangiocarcinoma
trastuzumab + lapatinib
Sensitive: B - Late Trials
trastuzumab + lapatinib
Sensitive
:
B
trastuzumab + lapatinib
Sensitive: B - Late Trials
trastuzumab + lapatinib
Sensitive
:
B
HER-2 expression
Colorectal Cancer
HER-2 expression
Colorectal Cancer
fam-trastuzumab deruxtecan-nxki
Sensitive: B - Late Trials
fam-trastuzumab deruxtecan-nxki
Sensitive
:
B
fam-trastuzumab deruxtecan-nxki
Sensitive: B - Late Trials
fam-trastuzumab deruxtecan-nxki
Sensitive
:
B
HER-2 expression
HER2 Positive Breast Cancer
HER-2 expression
HER2 Positive Breast Cancer
pertuzumab + ado-trastuzumab emtansine
Sensitive: B - Late Trials
pertuzumab + ado-trastuzumab emtansine
Sensitive
:
B
pertuzumab + ado-trastuzumab emtansine
Sensitive: B - Late Trials
pertuzumab + ado-trastuzumab emtansine
Sensitive
:
B
HER-2 expression
Endometrial Cancer
HER-2 expression
Endometrial Cancer
BNT323
Sensitive: B - Late Trials
BNT323
Sensitive
:
B
BNT323
Sensitive: B - Late Trials
BNT323
Sensitive
:
B
HER-2 expression
Endometrial Cancer
HER-2 expression
Endometrial Cancer
fam-trastuzumab deruxtecan-nxki
Sensitive: C1 - Off-label
fam-trastuzumab deruxtecan-nxki
Sensitive
:
C1
fam-trastuzumab deruxtecan-nxki
Sensitive: C1 - Off-label
fam-trastuzumab deruxtecan-nxki
Sensitive
:
C1
HER-2 expression
Gastroesophageal Junction Adenocarcinoma
HER-2 expression
Gastroesophageal Junction Adenocarcinoma
fam-trastuzumab deruxtecan-nxki
Sensitive: C1 - Off-label
fam-trastuzumab deruxtecan-nxki
Sensitive
:
C1
fam-trastuzumab deruxtecan-nxki
Sensitive: C1 - Off-label
fam-trastuzumab deruxtecan-nxki
Sensitive
:
C1
HER-2 expression
Salivary Gland Cancer
HER-2 expression
Salivary Gland Cancer
fam-trastuzumab deruxtecan-nxki
Sensitive: C1 - Off-label
fam-trastuzumab deruxtecan-nxki
Sensitive
:
C1
fam-trastuzumab deruxtecan-nxki
Sensitive: C1 - Off-label
fam-trastuzumab deruxtecan-nxki
Sensitive
:
C1
HER-2 expression
Uterine Cancer
HER-2 expression
Uterine Cancer
fam-trastuzumab deruxtecan-nxki
Sensitive: C1 - Off-label
fam-trastuzumab deruxtecan-nxki
Sensitive
:
C1
fam-trastuzumab deruxtecan-nxki
Sensitive: C1 - Off-label
fam-trastuzumab deruxtecan-nxki
Sensitive
:
C1
HER-2 expression
Non Small Cell Lung Cancer
HER-2 expression
Non Small Cell Lung Cancer
fam-trastuzumab deruxtecan-nxki
Sensitive: C1 - Off-label
fam-trastuzumab deruxtecan-nxki
Sensitive
:
C1
fam-trastuzumab deruxtecan-nxki
Sensitive: C1 - Off-label
fam-trastuzumab deruxtecan-nxki
Sensitive
:
C1
HER-2 expression
Breast Cancer
HER-2 expression
Breast Cancer
fam-trastuzumab deruxtecan-nxki
Sensitive: C1 - Off-label
fam-trastuzumab deruxtecan-nxki
Sensitive
:
C1
fam-trastuzumab deruxtecan-nxki
Sensitive: C1 - Off-label
fam-trastuzumab deruxtecan-nxki
Sensitive
:
C1
HER-2 expression
Biliary Tract Cancer
HER-2 expression
Biliary Tract Cancer
fam-trastuzumab deruxtecan-nxki
Sensitive: C1 - Off-label
fam-trastuzumab deruxtecan-nxki
Sensitive
:
C1
fam-trastuzumab deruxtecan-nxki
Sensitive: C1 - Off-label
fam-trastuzumab deruxtecan-nxki
Sensitive
:
C1
HER-2 expression
Pancreatic Cancer
HER-2 expression
Pancreatic Cancer
fam-trastuzumab deruxtecan-nxki
Sensitive: C1 - Off-label
fam-trastuzumab deruxtecan-nxki
Sensitive
:
C1
fam-trastuzumab deruxtecan-nxki
Sensitive: C1 - Off-label
fam-trastuzumab deruxtecan-nxki
Sensitive
:
C1
HER-2 expression
Bladder Cancer
HER-2 expression
Bladder Cancer
fam-trastuzumab deruxtecan-nxki
Sensitive: C1 - Off-label
fam-trastuzumab deruxtecan-nxki
Sensitive
:
C1
fam-trastuzumab deruxtecan-nxki
Sensitive: C1 - Off-label
fam-trastuzumab deruxtecan-nxki
Sensitive
:
C1
HER-2 expression
Ovarian Cancer
HER-2 expression
Ovarian Cancer
fam-trastuzumab deruxtecan-nxki
Sensitive: C1 - Off-label
fam-trastuzumab deruxtecan-nxki
Sensitive
:
C1
fam-trastuzumab deruxtecan-nxki
Sensitive: C1 - Off-label
fam-trastuzumab deruxtecan-nxki
Sensitive
:
C1
HER-2 expression
Cervical Cancer
HER-2 expression
Cervical Cancer
fam-trastuzumab deruxtecan-nxki
Sensitive: C1 - Off-label
fam-trastuzumab deruxtecan-nxki
Sensitive
:
C1
fam-trastuzumab deruxtecan-nxki
Sensitive: C1 - Off-label
fam-trastuzumab deruxtecan-nxki
Sensitive
:
C1
HER-2 expression
HER2 Positive Breast Cancer
HER-2 expression
HER2 Positive Breast Cancer
trastuzumab + pertuzumab
Sensitive: C2 – Inclusion Criteria
trastuzumab + pertuzumab
Sensitive
:
C2
trastuzumab + pertuzumab
Sensitive: C2 – Inclusion Criteria
trastuzumab + pertuzumab
Sensitive
:
C2
HER-2 expression
Gastric Cancer
HER-2 expression
Gastric Cancer
trastuzumab
Sensitive: C2 – Inclusion Criteria
trastuzumab
Sensitive
:
C2
trastuzumab
Sensitive: C2 – Inclusion Criteria
trastuzumab
Sensitive
:
C2
HER-2 expression
HER2 Positive Breast Cancer
HER-2 expression
HER2 Positive Breast Cancer
trastuzumab
Sensitive: C2 – Inclusion Criteria
trastuzumab
Sensitive
:
C2
trastuzumab
Sensitive: C2 – Inclusion Criteria
trastuzumab
Sensitive
:
C2
HER-2 expression
Gastric Cancer
HER-2 expression
Gastric Cancer
A166
Sensitive: C2 – Inclusion Criteria
A166
Sensitive
:
C2
A166
Sensitive: C2 – Inclusion Criteria
A166
Sensitive
:
C2
HER-2 expression
Breast Cancer
HER-2 expression
Breast Cancer
lapatinib
Sensitive: C2 – Inclusion Criteria
lapatinib
Sensitive
:
C2
lapatinib
Sensitive: C2 – Inclusion Criteria
lapatinib
Sensitive
:
C2
HER-2 expression
Colorectal Cancer
HER-2 expression
Colorectal Cancer
A166
Sensitive: C2 – Inclusion Criteria
A166
Sensitive
:
C2
A166
Sensitive: C2 – Inclusion Criteria
A166
Sensitive
:
C2
HER-2 expression
HER2 Positive Breast Cancer
HER-2 expression
HER2 Positive Breast Cancer
A166
Sensitive: C2 – Inclusion Criteria
A166
Sensitive
:
C2
A166
Sensitive: C2 – Inclusion Criteria
A166
Sensitive
:
C2
HER-2 expression
HER2 Positive Breast Cancer
HER-2 expression
HER2 Positive Breast Cancer
avelumab
Sensitive: C2 – Inclusion Criteria
avelumab
Sensitive
:
C2
avelumab
Sensitive: C2 – Inclusion Criteria
avelumab
Sensitive
:
C2
HER-2 expression
Colorectal Cancer
HER-2 expression
Colorectal Cancer
cetuximab
Sensitive: C2 – Inclusion Criteria
cetuximab
Sensitive
:
C2
cetuximab
Sensitive: C2 – Inclusion Criteria
cetuximab
Sensitive
:
C2
HER-2 expression
Solid Tumor
HER-2 expression
Solid Tumor
SBT6050
Sensitive: C2 – Inclusion Criteria
SBT6050
Sensitive
:
C2
SBT6050
Sensitive: C2 – Inclusion Criteria
SBT6050
Sensitive
:
C2
HER-2 expression
Gastric Cancer
HER-2 expression
Gastric Cancer
AST-301
Sensitive: C2 – Inclusion Criteria
AST-301
Sensitive
:
C2
AST-301
Sensitive: C2 – Inclusion Criteria
AST-301
Sensitive
:
C2
HER-2 expression
Gastric Cancer
HER-2 expression
Gastric Cancer
disitamab vedotin
Sensitive: C2 – Inclusion Criteria
disitamab vedotin
Sensitive
:
C2
disitamab vedotin
Sensitive: C2 – Inclusion Criteria
disitamab vedotin
Sensitive
:
C2
HER-2 expression
Gastroesophageal Junction Adenocarcinoma
HER-2 expression
Gastroesophageal Junction Adenocarcinoma
KN026
Sensitive: C2 – Inclusion Criteria
KN026
Sensitive
:
C2
KN026
Sensitive: C2 – Inclusion Criteria
KN026
Sensitive
:
C2
^
^
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