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BIOMARKER:
EGFRvIII mutation
i
Other names:
EGFR, ERBB, ERBB1, Epidermal growth factor receptor
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Entrez ID:
1956
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
EGFR exon 19 deletion (79)
EGFR amplification (52)
EGFR exon 18 deletion (3)
EGFR exon 2-7 deletion + EGFR amplification (2)
EGFR amplification + ERBB2 amplification (1)
EGFR exon 19 deletion + HER-2 amplification (1)
EGFR exon 21 deletion (1)
EGFR T790M + exon 19 deletion (0)
EGFR amplifcation (0)
EGFR exon 19 deletion (79)
EGFR amplification (52)
EGFR exon 18 deletion (3)
EGFR exon 2-7 deletion + EGFR amplification (2)
EGFR amplification + ERBB2 amplification (1)
EGFR exon 19 deletion + HER-2 amplification (1)
EGFR exon 21 deletion (1)
EGFR T790M + exon 19 deletion (0)
EGFR amplifcation (0)
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Associations
News
Trials
VERI cancer hierarchy
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EGFRvIII mutation
Squamous Cell Carcinoma of Head and Neck
EGFRvIII mutation
Squamous Cell Carcinoma of Head and Neck
cetuximab
Resistant: C3 – Early Trials
cetuximab
Resistant
:
C3
cetuximab
Resistant: C3 – Early Trials
cetuximab
Resistant
:
C3
EGFRvIII mutation
Glioblastoma
EGFRvIII mutation
Glioblastoma
erlotinib
Resistant: C3 – Early Trials
erlotinib
Resistant
:
C3
erlotinib
Resistant: C3 – Early Trials
erlotinib
Resistant
:
C3
EGFRvIII mutation
Astrocytoma
EGFRvIII mutation
Astrocytoma
WSD0922
Sensitive: C3 – Early Trials
WSD0922
Sensitive
:
C3
WSD0922
Sensitive: C3 – Early Trials
WSD0922
Sensitive
:
C3
EGFRvIII mutation
Glioblastoma
EGFRvIII mutation
Glioblastoma
AMG 595
Sensitive: C3 – Early Trials
AMG 595
Sensitive
:
C3
AMG 595
Sensitive: C3 – Early Trials
AMG 595
Sensitive
:
C3
EGFRvIII mutation
Glioblastoma
EGFRvIII mutation
Glioblastoma
EGFRvIII-targeted CAR-T immunotherapy
Sensitive: D – Preclinical
EGFRvIII-targeted CAR-T immunotherapy
Sensitive
:
D
EGFRvIII-targeted CAR-T immunotherapy
Sensitive: D – Preclinical
EGFRvIII-targeted CAR-T immunotherapy
Sensitive
:
D
EGFRvIII mutation
Glioma
EGFRvIII mutation
Glioma
Bay846
Sensitive: D – Preclinical
Bay846
Sensitive
:
D
Bay846
Sensitive: D – Preclinical
Bay846
Sensitive
:
D
EGFRvIII mutation
Non Small Cell Lung Cancer
EGFRvIII mutation
Non Small Cell Lung Cancer
gefitinib
Sensitive: D – Preclinical
gefitinib
Sensitive
:
D
gefitinib
Sensitive: D – Preclinical
gefitinib
Sensitive
:
D
EGFRvIII mutation
Solid Tumor
EGFRvIII mutation
Solid Tumor
TAS2940
Sensitive: D – Preclinical
TAS2940
Sensitive
:
D
TAS2940
Sensitive: D – Preclinical
TAS2940
Sensitive
:
D
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