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BIOMARKER:
EGFR mutation + YES1 overexpression
i
Other names:
EGFR, ERBB, ERBB1, Epidermal growth factor receptor, YES1, YES Proto-Oncogene 1, Src Family Tyrosine Kinase, V-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1, Tyrosine-Protein Kinase Yes, Proto-Oncogene C-Yes, YES1 Proto-Oncogene, Src Family Tyrosine Kinase, Proto-Oncogene Tyrosine-Protein Kinase YES, Yamaguchi Sarcoma Oncogene, Cellular Yes-1 Protein, P61-YES, P61-Yes, HsT441, C-Yes
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Entrez ID:
1956
;
7525
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
EGFR exon 19 deletion (79)
EGFR amplification (52)
YES1 amplification (5)
EGFR exon 18 deletion (3)
EGFR exon 2-7 deletion + EGFR amplification (2)
EGFR amplification + ERBB2 amplification (1)
EGFR exon 19 deletion + HER-2 amplification (1)
EGFR exon 21 deletion (1)
EGFR T790M + exon 19 deletion (0)
EGFR amplifcation (0)
YES1 amplification + HER-2 amplification (0)
EGFR exon 19 deletion (79)
EGFR amplification (52)
YES1 amplification (5)
EGFR exon 18 deletion (3)
EGFR exon 2-7 deletion + EGFR amplification (2)
EGFR amplification + ERBB2 amplification (1)
EGFR exon 19 deletion + HER-2 amplification (1)
EGFR exon 21 deletion (1)
EGFR T790M + exon 19 deletion (0)
EGFR amplifcation (0)
YES1 amplification + HER-2 amplification (0)
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EGFR mutation + YES1 overexpression
Lung Adenocarcinoma
EGFR mutation + YES1 overexpression
Lung Adenocarcinoma
repotrectinib
Sensitive: D – Preclinical
repotrectinib
Sensitive
:
D
repotrectinib
Sensitive: D – Preclinical
repotrectinib
Sensitive
:
D
EGFR mutation + YES1 overexpression
Lung Adenocarcinoma
EGFR mutation + YES1 overexpression
Lung Adenocarcinoma
dasatinib
Sensitive: D – Preclinical
dasatinib
Sensitive
:
D
dasatinib
Sensitive: D – Preclinical
dasatinib
Sensitive
:
D
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