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BIOMARKER:
YES1 amplification
i
Other names:
YES1, YES Proto-Oncogene 1, Src Family Tyrosine Kinase, V-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1, Tyrosine-Protein Kinase Yes, Proto-Oncogene C-Yes, YES1 Proto-Oncogene, Src Family Tyrosine Kinase, Proto-Oncogene Tyrosine-Protein Kinase YES, Yamaguchi Sarcoma Oncogene, Cellular Yes-1 Protein, P61-YES, P61-Yes, HsT441, C-Yes
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Entrez ID:
7525
Related biomarkers:
Expression
CNA
Others
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Trials
VERI cancer hierarchy
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YES1 amplification
Breast Cancer
YES1 amplification
Breast Cancer
neratinib
Resistant: D – Preclinical
neratinib
Resistant
:
D
neratinib
Resistant: D – Preclinical
neratinib
Resistant
:
D
YES1 amplification
HER2 Positive Breast Cancer
YES1 amplification
HER2 Positive Breast Cancer
ado-trastuzumab emtansine
Resistant: D – Preclinical
ado-trastuzumab emtansine
Resistant
:
D
ado-trastuzumab emtansine
Resistant: D – Preclinical
ado-trastuzumab emtansine
Resistant
:
D
YES1 amplification
Breast Cancer
YES1 amplification
Breast Cancer
dasatinib + ado-trastuzumab emtansine
Sensitive: D – Preclinical
dasatinib + ado-trastuzumab emtansine
Sensitive
:
D
dasatinib + ado-trastuzumab emtansine
Sensitive: D – Preclinical
dasatinib + ado-trastuzumab emtansine
Sensitive
:
D
YES1 amplification
HER2 Positive Breast Cancer
YES1 amplification
HER2 Positive Breast Cancer
trastuzumab
Resistant: D – Preclinical
trastuzumab
Resistant
:
D
trastuzumab
Resistant: D – Preclinical
trastuzumab
Resistant
:
D
YES1 amplification
Esophageal Squamous Cell Carcinoma
YES1 amplification
Esophageal Squamous Cell Carcinoma
NXP900
Sensitive: D – Preclinical
NXP900
Sensitive
:
D
NXP900
Sensitive: D – Preclinical
NXP900
Sensitive
:
D
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