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BIOMARKER:
EGFR mutation + NRAS Q61K
i
Other names:
EGFR, ERBB, ERBB1, Epidermal growth factor receptor, NRAS1, N-Ras Protein Part 4, Neuroblastoma RAS Viral (V-Ras) Oncogene Homolog, NRAS, Neuroblastoma RAS Viral Oncogene Homolog, NRAS Proto-Oncogene, GTPase
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Entrez ID:
1956
;
4893
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
EGFR exon 19 deletion (79)
EGFR amplification (52)
NRAS amplification (4)
EGFR exon 18 deletion (3)
EGFR exon 2-7 deletion + EGFR amplification (2)
EGFR amplification + ERBB2 amplification (1)
EGFR exon 19 deletion + HER-2 amplification (1)
EGFR exon 21 deletion (1)
EGFR T790M + exon 19 deletion (0)
EGFR amplifcation (0)
EGFR exon 19 deletion (79)
EGFR amplification (52)
NRAS amplification (4)
EGFR exon 18 deletion (3)
EGFR exon 2-7 deletion + EGFR amplification (2)
EGFR amplification + ERBB2 amplification (1)
EGFR exon 19 deletion + HER-2 amplification (1)
EGFR exon 21 deletion (1)
EGFR T790M + exon 19 deletion (0)
EGFR amplifcation (0)
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EGFR mutation + NRAS Q61K
Lung Adenocarcinoma
EGFR mutation + NRAS Q61K
Lung Adenocarcinoma
trametinib + erlotinib
Sensitive: D – Preclinical
trametinib + erlotinib
Sensitive
:
D
trametinib + erlotinib
Sensitive: D – Preclinical
trametinib + erlotinib
Sensitive
:
D
EGFR mutation + NRAS Q61K
Lung Adenocarcinoma
EGFR mutation + NRAS Q61K
Lung Adenocarcinoma
erlotinib
Resistant: D – Preclinical
erlotinib
Resistant
:
D
erlotinib
Resistant: D – Preclinical
erlotinib
Resistant
:
D
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