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BIOMARKER:
EGFR mutation + BRAF V600
i
Other names:
EGFR, ERBB, ERBB1, Epidermal growth factor receptor, BRAF, B-raf proto-oncogene, B-raf proto-oncogene, Serine/threonine kinase, V-Raf murine sarcoma viral oncogene homolog B, Serine/threonine-protein kinase B-Raf, Proto-oncogene B-Raf, BRAF1, RAFB1, B-raf proto-oncogene Serine/threonine-protein kinase, Murine sarcoma viral (V-Raf) oncogene homolog B1, B-raf serine/threonine-protein, 94 KDa B-raf protein, B-RAF1
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Entrez ID:
1956
;
673
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
EGFR exon 19 deletion (79)
EGFR amplification (52)
BRAF L485-P490 deletion (6)
EGFR exon 18 deletion (3)
EGFR exon 2-7 deletion + EGFR amplification (2)
EGFR amplification + ERBB2 amplification (1)
EGFR exon 19 deletion + HER-2 amplification (1)
EGFR exon 21 deletion (1)
BRAF amplification (1)
EGFR T790M + exon 19 deletion (0)
EGFR amplifcation (0)
EGFR exon 19 deletion (79)
EGFR amplification (52)
BRAF L485-P490 deletion (6)
EGFR exon 18 deletion (3)
EGFR exon 2-7 deletion + EGFR amplification (2)
EGFR amplification + ERBB2 amplification (1)
EGFR exon 19 deletion + HER-2 amplification (1)
EGFR exon 21 deletion (1)
BRAF amplification (1)
EGFR T790M + exon 19 deletion (0)
EGFR amplifcation (0)
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Associations
News
Trials
VERI cancer hierarchy
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EGFR mutation + BRAF V600
Lung Adenocarcinoma
EGFR mutation + BRAF V600
Lung Adenocarcinoma
trametinib + osimertinib + dabrafenib
Sensitive: C4 – Case Studies
trametinib + osimertinib + dabrafenib
Sensitive
:
C4
trametinib + osimertinib + dabrafenib
Sensitive: C4 – Case Studies
trametinib + osimertinib + dabrafenib
Sensitive
:
C4
EGFR mutation + BRAF V600
Lung Adenocarcinoma
EGFR mutation + BRAF V600
Lung Adenocarcinoma
osimertinib
Resistant: C4 – Case Studies
osimertinib
Resistant
:
C4
osimertinib
Resistant: C4 – Case Studies
osimertinib
Resistant
:
C4
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