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Association details:
Biomarker:
No biomarker
Cancer:
B Acute Lymphoblastic Leukemia
Drug:
Blincyto (blinatumomab)
(
CD3 agonist
,
CD19 inhibitor
) +
Besponsa (inotuzumab ozogamicin)
(
DNA replication inhibitor
,
CD22-targeted antibody-drug conjugate
)
Direction:
Sensitive
Evidence:
Evidence Level:
Sensitive: A2 - Guideline
Source:
NCCN
Published date:
04/04/2022
Excerpt:
Acute Lymphoblastic Leukemia...Other Recommended Regimens...Inotuzumab ozogamicins + mini-hyperCVD ± blinatumomabs (for B-ALL only) (cyclophosphamide, dexamethasone, vincristine, methotrexate, cytarabine)
Secondary therapy:
cytarabine; Mini-HCVD; vincristine; cyclophosphamide; methotrexate; dexamethasone
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