The AML1/ETO (RUNX1/RUNX1T1) Translocation, Dual Fusion FISH Probe Kit consists of a 156kb probe labeled in Texas Red, centromeric to the AML1 (RUNX1) gene, including the CLIC6 gene; a 169kb probe labelled in Texas red, telomeric to AML1 (RUNX1) gene, extending beyond the marker D21S1921; and two (151kb and 194kb) probes, labeled inn FITC green, on either side of the ETO (RUNX1T1) gene.
Acute Myelogenous Leukemia
RUNX1 (RUNX Family Transcription Factor 1), RUNX1T1 (RUNX1 Partner Transcriptional Co-Repressor 1)
Fluorescence in situ hybridization (FISH)