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our Premium Content: News alerts, weekly reports and conference plannersTEST:SafeSEQ CRC MRD assay
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News alerts, weekly reports and conference planners
Company:
Sysmex CorpType:
Laboratory Developed Test
Related tests:
SafeSEQ CRC MRD assay that detects mutations in 14 genes relevant in CRC, including AKT1, APC, BRAF, CTNNB1, ERBB3, FBXW7, KRAS, NRAS, PIK3CA, POLE, PPP2R1A, RNF43, SMAD4 and TP53. Tumour sequencing used an amplicon-based NGS 59-gene custom panel.
Cancer:
Colorectal Cancer
Gene:
AKT1 (V-akt murine thymoma viral oncogene homolog 1), APC (APC Regulator Of WNT Signaling Pathway), BRAF (B-raf proto-oncogene), CTNNB1 (Catenin (cadherin-associated protein), beta 1), ERBB3 (V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3), FBXW7 (F-Box And WD Repeat Domain Containing 7)
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AKT1 (V-akt murine thymoma viral oncogene homolog 1), APC (APC Regulator Of WNT Signaling Pathway), BRAF (B-raf proto-oncogene), CTNNB1 (Catenin (cadherin-associated protein), beta 1), ERBB3 (V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3), FBXW7 (F-Box And WD Repeat Domain Containing 7), KRAS (KRAS proto-oncogene GTPase), NRAS (Neuroblastoma RAS viral oncogene homolog), PIK3CA (Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha), POLE (DNA Polymerase Epsilon), RNF43 (Ring Finger Protein 43), SMAD4 (SMAD family member 4), TP53 (Tumor protein P53)
Method:
Next-Generation Sequencing (NGS)
Confirmatory trial(s)
Confirmatory trial(s)
