OncoBEAMTM EGFR v2 covers substantially more mutations in the epidermal growth factor receptor (EGFR) gene than its predecessor. It enables detection of 36 cancer-relevant EGFR mutations present in ctDNA extracted from plasma including sensitizing mutations such as exon 19 deletions, L858R, G719X and L861Q, as well as the T790M resistance mutation and multiple C797S variants.