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Company:
NeoGenomicsType:
Laboratory Developed Test
Related tests:
NexCourse Complete is a multi-gene molecular profiling assay covering genes implicated in the pathogenesis of solid and/or hematological malignancies. There are key genes that are recurrently mutated in various human cancers. Genomic DNA is isolated from bone marrow, aspirates, peripheral blood or formalin fixed paraffin embedded tissue and the DNA sequence of targeted regions of 236 genes.
Cancer:
Hematological Malignancies, Solid Tumor
Gene:
ABL1 (ABL proto-oncogene 1), ABL2 (ABL Proto-Oncogene 2, Non-Receptor Tyrosine Kinase), AKT1 (V-akt murine thymoma viral oncogene homolog 1), AKT2 (V-akt murine thymoma viral oncogene homolog 2), AKT3 (V-akt murine thymoma viral oncogene homolog 3), ALK (Anaplastic lymphoma kinase)
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ABL1 (ABL proto-oncogene 1), ABL2 (ABL Proto-Oncogene 2, Non-Receptor Tyrosine Kinase), AKT1 (V-akt murine thymoma viral oncogene homolog 1), AKT2 (V-akt murine thymoma viral oncogene homolog 2), AKT3 (V-akt murine thymoma viral oncogene homolog 3), ALK (Anaplastic lymphoma kinase), APC (APC Regulator Of WNT Signaling Pathway), AR (Androgen receptor), ARAF (A-Raf Proto-Oncogene), BCL2L11, BIRC3 (Baculoviral IAP repeat containing 3), BRAF (B-raf proto-oncogene), BRCA1 (Breast cancer 1, early onset), BRCA2 (Breast cancer 2, early onset), CDH1 (Cadherin 1), CDK2 (Cyclin-dependent kinase 2), IKZF1 (IKAROS Family Zinc Finger 1), IKZF3 (IKAROS Family Zinc Finger 3), JAK1 (Janus Kinase 1), JAK2 (Janus kinase 2), JAK3 (Janus Kinase 3), NTRK1 (Neurotrophic tyrosine kinase, receptor, type 1), NTRK2 (Neurotrophic tyrosine kinase, receptor, type 2), NTRK3 (Neurotrophic tyrosine kinase, receptor, type 3), PDGFRA (Platelet Derived Growth Factor Receptor Alpha), PTEN (Phosphatase and tensin homolog), ROS1 (Proto-Oncogene Tyrosine-Protein Kinase ROS), TSC1 (TSC complex subunit 1), VHL (von Hippel-Lindau tumor suppressor), mTOR (Mechanistic target of rapamycin kinase)
Method:
Next-Generation Sequencing (NGS)
