The allele burden of JAK2 V617F was significantly lower in ET than in PV and PMF. Only the WBC, Hct and Plt counts were significantly different among the JAK2 V617F allele burden subgroups. Measuring the JAK2 V617F allele burden quantitatively might be an additional tool for predicting the hematological outcomes of MPNs.
"QIAGEN N.V...today announced the certification of its leading in-vitro diagnostic (IVD) kit and its fully automated NeuMoDx platforms under the European Union’s new In-Vitro Diagnostic Medical Devices Regulation (IVDR) replacing the previous IVDD rules since May. The ipsogen JAK2 RGQ PCR Kit used for myeloproliferative neoplasms (MPN), a certain type of blood cancer, is now QIAGEN’s first IVD kit with IVDR CE-marking under Class C."