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The c-Kit pharmDx assay is a qualitative immunohistochemical (IHC) kit system used manually and on the Dako Autostainer, for the identification of c-kit protein/CD117 antigen (c-kit protein) expression in normal and neoplastic formalin-fixed paraffin-embedded tissues for histological evaluation. The c-Kit pharmDx rabbit polyclonal antibodies specifically detect the c-kit protein in CD117 antigen-expressing cells. This test is indicated as an aid in the differential diagnosis of gastrointestinal stromal tumors (GIST).
Cancer:
Gastrointestinal Stromal Tumor
Gene:
KIT (KIT proto-oncogene, receptor tyrosine kinase)
Drug:
imatinib
Method:
Immunohistochemistry (IHC)
Approvals
Date
Cancer
Gene
Drug
By
06/27/05
FDA