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    EGFR pharmDx Kit is a qualitative immunohistochemical kit system that includes all reagents necessary to identify expression of epidermal growth factor receptor (EGFR) protein on the surface of normal and neoplastic cells. EGFR protein is also called HER1 protein. Through the use of standard methods and reagents, EGFR pharmDx Kit will provide reproducible results from laboratory to laboratory. EGFR is indicated as an aid in identifying colorectal cancer patients eligible for treatment with Erbitux® (cetuximab) or Vectibix™ (panitumumab). The kit utilizes a simple two-step staining procedure and is suitable for formalin-fixed, paraffin-embedded specimens.
    Cancer:
    Colorectal Cancer
    Gene:
    EGFR (Epidermal growth factor receptor)
    Drug:
    Erbitux (cetuximab), Vectibix (panitumumab)
    Method:
    Immunohistochemistry (IHC)
    Approvals
    Date
    Cancer
    Gene
    Drug
    By
    02/12/04
    CRC
    EGFR
    cetuximab
    FDA
    09/27/06
    CRC
    EGFR
    panitumumab
    FDA