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    1year
    ENOX2 inhibition enhances infiltration of effector memory T-cell and mediates response to chemotherapy in immune-quiescent cancer. (PubMed, J Adv Res)
    Tumor-intrinsic ENOX2 expression is associated with tumor phenotype and PFS in NPC. Targeting ENOX2 with IDX and cisplatin impose qualitative control of T-cell response by preferentially increasing immune cells infiltration, Tem differentiation and tumor suppression. We suggest that ENOX2 inhibition may be a promising therapeutic strategy to enhance the effects of chemotherapy.
    Journal
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    CD8 (cluster of differentiation 8)
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    cisplatin • Veyonda (idronoxil) • phenoxodiol (NV06)