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DRUG:
Truqap (capivasertib)
i
Other names:
AZD5363, AZD 5363, AZD-5363
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Associations
(37)
News
Trials
Company:
AstraZeneca, Otsuka
Drug class:
AKT inhibitor
Related drugs:
‹
MK-2206 (27)
RG7440 (27)
chidamide (23)
LY294002 (7)
TAS-117 (7)
pexidartinib (6)
ONC201 (5)
DIACC3010 (5)
GSK690693 (3)
enzastaurin (3)
GDC-0084 (3)
CCT128930 (2)
SBI-756 (2)
UCN-01 (1)
DFN-529 (1)
EC-70124 (1)
LY2780301 (1)
SBI-726 (1)
nelfinavir (1)
D21266 (1)
CBL0102 (1)
LAE003 (1)
A 443654 (0)
AT7867 (0)
HV-107 (0)
antroquinonol (0)
MKC-1 (0)
SR13668 (0)
TAS0612 (0)
NSC311152 (0)
inhibitors of the PI3K/AKT/mTOR pathway (0)
PBI-05204 (0)
NV06 (0)
PX 866 (0)
PTX-200 (0)
MK-2206 (27)
RG7440 (27)
chidamide (23)
LY294002 (7)
TAS-117 (7)
pexidartinib (6)
ONC201 (5)
DIACC3010 (5)
GSK690693 (3)
enzastaurin (3)
GDC-0084 (3)
CCT128930 (2)
SBI-756 (2)
UCN-01 (1)
DFN-529 (1)
EC-70124 (1)
LY2780301 (1)
SBI-726 (1)
nelfinavir (1)
D21266 (1)
CBL0102 (1)
LAE003 (1)
A 443654 (0)
AT7867 (0)
HV-107 (0)
antroquinonol (0)
MKC-1 (0)
SR13668 (0)
TAS0612 (0)
NSC311152 (0)
inhibitors of the PI3K/AKT/mTOR pathway (0)
PBI-05204 (0)
NV06 (0)
PX 866 (0)
PTX-200 (0)
›
Associations
(37)
News
Trials
VERI cancer hierarchy
Reset Filters
PIK3CA mutation + ER positive
HER2 Negative Breast Cancer
PIK3CA mutation + ER positive
HER2 Negative Breast Cancer
capivasertib
Sensitive: A1 - Approval
capivasertib
Sensitive
:
A1
capivasertib
Sensitive: A1 - Approval
capivasertib
Sensitive
:
A1
HR positive
HER2 Negative Breast Cancer
HR positive
HER2 Negative Breast Cancer
capivasertib
Sensitive: A1 - Approval
capivasertib
Sensitive
:
A1
capivasertib
Sensitive: A1 - Approval
capivasertib
Sensitive
:
A1
AKT1 mutation + HR positive
HER2 Negative Breast Cancer
AKT1 mutation + HR positive
HER2 Negative Breast Cancer
capivasertib
Sensitive: A1 - Approval
capivasertib
Sensitive
:
A1
capivasertib
Sensitive: A1 - Approval
capivasertib
Sensitive
:
A1
PIK3CA mutation + HR positive
HER2 Negative Breast Cancer
PIK3CA mutation + HR positive
HER2 Negative Breast Cancer
capivasertib
Sensitive: A1 - Approval
capivasertib
Sensitive
:
A1
capivasertib
Sensitive: A1 - Approval
capivasertib
Sensitive
:
A1
PTEN mutation + HR positive
HER2 Negative Breast Cancer
PTEN mutation + HR positive
HER2 Negative Breast Cancer
capivasertib
Sensitive: A1 - Approval
capivasertib
Sensitive
:
A1
capivasertib
Sensitive: A1 - Approval
capivasertib
Sensitive
:
A1
PTEN deletion + ER positive
HER2 Negative Breast Cancer
PTEN deletion + ER positive
HER2 Negative Breast Cancer
capivasertib
Sensitive: A1 - Approval
capivasertib
Sensitive
:
A1
capivasertib
Sensitive: A1 - Approval
capivasertib
Sensitive
:
A1
AKT1 mutation + ER positive
HER2 Negative Breast Cancer
AKT1 mutation + ER positive
HER2 Negative Breast Cancer
capivasertib
Sensitive: A1 - Approval
capivasertib
Sensitive
:
A1
capivasertib
Sensitive: A1 - Approval
capivasertib
Sensitive
:
A1
AKT1 mutation + ER positive
Breast Cancer
AKT1 mutation + ER positive
Breast Cancer
capivasertib
Sensitive: C1 - Off-label
capivasertib
Sensitive
:
C1
capivasertib
Sensitive: C1 - Off-label
capivasertib
Sensitive
:
C1
BRCA2 mutation
Breast Cancer
BRCA2 mutation
Breast Cancer
olaparib + capivasertib
Sensitive: C2 – Inclusion Criteria
olaparib + capivasertib
Sensitive
:
C2
olaparib + capivasertib
Sensitive: C2 – Inclusion Criteria
olaparib + capivasertib
Sensitive
:
C2
BRCA2 mutation
Prostate Cancer
BRCA2 mutation
Prostate Cancer
olaparib + capivasertib
Sensitive: C2 – Inclusion Criteria
olaparib + capivasertib
Sensitive
:
C2
olaparib + capivasertib
Sensitive: C2 – Inclusion Criteria
olaparib + capivasertib
Sensitive
:
C2
BRCA1 mutation
Prostate Cancer
BRCA1 mutation
Prostate Cancer
olaparib + capivasertib
Sensitive: C2 – Inclusion Criteria
olaparib + capivasertib
Sensitive
:
C2
olaparib + capivasertib
Sensitive: C2 – Inclusion Criteria
olaparib + capivasertib
Sensitive
:
C2
PIK3CA mutation
Gastric Cancer
PIK3CA mutation
Gastric Cancer
capivasertib
Sensitive: C2 – Inclusion Criteria
capivasertib
Sensitive
:
C2
capivasertib
Sensitive: C2 – Inclusion Criteria
capivasertib
Sensitive
:
C2
BRCA1 mutation
Breast Cancer
BRCA1 mutation
Breast Cancer
olaparib + capivasertib
Sensitive: C2 – Inclusion Criteria
olaparib + capivasertib
Sensitive
:
C2
olaparib + capivasertib
Sensitive: C2 – Inclusion Criteria
olaparib + capivasertib
Sensitive
:
C2
PTEN mutation
Estrogen Receptor Positive Breast Cancer
PTEN mutation
Estrogen Receptor Positive Breast Cancer
capivasertib
Sensitive: C2 – Inclusion Criteria
capivasertib
Sensitive
:
C2
capivasertib
Sensitive: C2 – Inclusion Criteria
capivasertib
Sensitive
:
C2
AKT1 E17K
Salivary Gland Cancer
AKT1 E17K
Salivary Gland Cancer
capivasertib
Sensitive: C3 – Early Trials
capivasertib
Sensitive
:
C3
capivasertib
Sensitive: C3 – Early Trials
capivasertib
Sensitive
:
C3
AKT1 E17K + HR positive
HER2 Negative Breast Cancer
AKT1 E17K + HR positive
HER2 Negative Breast Cancer
capivasertib
Sensitive: C3 – Early Trials
capivasertib
Sensitive
:
C3
capivasertib
Sensitive: C3 – Early Trials
capivasertib
Sensitive
:
C3
AKT1 E17K
Uterine Corpus Leiomyosarcoma
AKT1 E17K
Uterine Corpus Leiomyosarcoma
capivasertib
Sensitive: C3 – Early Trials
capivasertib
Sensitive
:
C3
capivasertib
Sensitive: C3 – Early Trials
capivasertib
Sensitive
:
C3
AKT1 mutation + ER negative
Breast Cancer
AKT1 mutation + ER negative
Breast Cancer
capivasertib
Sensitive: C3 – Early Trials
capivasertib
Sensitive
:
C3
capivasertib
Sensitive: C3 – Early Trials
capivasertib
Sensitive
:
C3
TP53 mutation
Ovarian Cancer
TP53 mutation
Ovarian Cancer
olaparib + capivasertib
Sensitive: C3 – Early Trials
olaparib + capivasertib
Sensitive
:
C3
olaparib + capivasertib
Sensitive: C3 – Early Trials
olaparib + capivasertib
Sensitive
:
C3
BRCA2 mutation
Ovarian Cancer
BRCA2 mutation
Ovarian Cancer
olaparib + capivasertib
Sensitive: C3 – Early Trials
olaparib + capivasertib
Sensitive
:
C3
olaparib + capivasertib
Sensitive: C3 – Early Trials
olaparib + capivasertib
Sensitive
:
C3
BRCA1 mutation
Ovarian Cancer
BRCA1 mutation
Ovarian Cancer
olaparib + capivasertib
Sensitive: C3 – Early Trials
olaparib + capivasertib
Sensitive
:
C3
olaparib + capivasertib
Sensitive: C3 – Early Trials
olaparib + capivasertib
Sensitive
:
C3
AKT1 E17K
Breast Cancer
AKT1 E17K
Breast Cancer
capivasertib
Sensitive: C3 – Early Trials
capivasertib
Sensitive
:
C3
capivasertib
Sensitive: C3 – Early Trials
capivasertib
Sensitive
:
C3
AKT1 E17K
Estrogen Receptor Positive Breast Cancer
AKT1 E17K
Estrogen Receptor Positive Breast Cancer
capivasertib
Sensitive: C3 – Early Trials
capivasertib
Sensitive
:
C3
capivasertib
Sensitive: C3 – Early Trials
capivasertib
Sensitive
:
C3
AKT1 E17K
Solid Tumor
AKT1 E17K
Solid Tumor
capivasertib
Sensitive: C3 – Early Trials
capivasertib
Sensitive
:
C3
capivasertib
Sensitive: C3 – Early Trials
capivasertib
Sensitive
:
C3
PTEN deletion + BRCA1 mutation
Breast Cancer
PTEN deletion + BRCA1 mutation
Breast Cancer
olaparib + durvalumab + capivasertib
Sensitive: C3 – Early Trials
olaparib + durvalumab + capivasertib
Sensitive
:
C3
olaparib + durvalumab + capivasertib
Sensitive: C3 – Early Trials
olaparib + durvalumab + capivasertib
Sensitive
:
C3
PIK3CA E545K
Breast Cancer
PIK3CA E545K
Breast Cancer
olaparib + durvalumab + capivasertib
Sensitive: C3 – Early Trials
olaparib + durvalumab + capivasertib
Sensitive
:
C3
olaparib + durvalumab + capivasertib
Sensitive: C3 – Early Trials
olaparib + durvalumab + capivasertib
Sensitive
:
C3
ER positive
HER2 Negative Breast Cancer
ER positive
HER2 Negative Breast Cancer
capivasertib
Sensitive: C3 – Early Trials
capivasertib
Sensitive
:
C3
capivasertib
Sensitive: C3 – Early Trials
capivasertib
Sensitive
:
C3
ER positive
HER2 Negative Breast Cancer
ER positive
HER2 Negative Breast Cancer
capivasertib + AZD9833
Sensitive: C3 – Early Trials
capivasertib + AZD9833
Sensitive
:
C3
capivasertib + AZD9833
Sensitive: C3 – Early Trials
capivasertib + AZD9833
Sensitive
:
C3
PTEN deletion
Gastric Cancer
PTEN deletion
Gastric Cancer
capivasertib
Sensitive: D – Preclinical
capivasertib
Sensitive
:
D
capivasertib
Sensitive: D – Preclinical
capivasertib
Sensitive
:
D
MTOR H1968Y
Melanoma
MTOR H1968Y
Melanoma
capivasertib
Sensitive: D – Preclinical
capivasertib
Sensitive
:
D
capivasertib
Sensitive: D – Preclinical
capivasertib
Sensitive
:
D
MTOR S2215Y
Melanoma
MTOR S2215Y
Melanoma
capivasertib
Sensitive: D – Preclinical
capivasertib
Sensitive
:
D
capivasertib
Sensitive: D – Preclinical
capivasertib
Sensitive
:
D
PTEN deletion
Prostate Cancer
PTEN deletion
Prostate Cancer
enzalutamide capsule + capivasertib
Sensitive: D – Preclinical
enzalutamide capsule + capivasertib
Sensitive
:
D
enzalutamide capsule + capivasertib
Sensitive: D – Preclinical
enzalutamide capsule + capivasertib
Sensitive
:
D
^
^
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