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    DRUG:

    nanoparticle-actinomycin D (NP-ACT D)

    i
    Other names: NP-ACT D, RASP-101
    Associations

    News

    Trials
    Company:
    Rasna Therap, Tiziana Life Sci
    Drug class:
    Topoisomerase II inhibitor, RNA synthesis inhibitor
    Related drugs:
    Associations

    News

    Trials
    9ms
    Albumin pre-opsonized membrane-active iPep nanomedicine potentiates chemo to immunotherapy of cancer. (PubMed, Biomaterials)
    In a challenging orthotopic breast cancer model, boost i. v. injections of NP acted as in situ tumor vaccine that drastically enhanced 4T1-specific cellular and humoral immunities to reverse disease progression. Thus, with combined effects of direct cytoreduction, immune activation and tumor vaccine, iPep-NP presents the promise and potential of a new modality of cancer medicine.
    Journal
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    nanoparticle-actinomycin D (NP-ACT D)