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DRUG:

Pixuvri (pixantrone)

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Company:

Servier

Drug class:

Topoisomerase II inhibitor

Related drugs:

doxorubicin hydrochloride (87)

etoposide IV (53)

etoposide oral (33)

pegylated liposomal doxorubicin (31)

epirubicin (29)

daunorubicin (20)

cytarabine/daunorubicin liposomal formulation (19)

idarubicin hydrochloride (16)

mitoxantrone (16)

dactinomycin (8)

non-pegylated liposomal doxorubicin (3)

pegylated liposomal doxorubicin (1)

zoptarelin doxorubicin (1)

mitoxantrone liposomal (0)

H-ferritin–nanocaged doxorubicin (0)

non-pegylated liposomal doxorubicin (0)

lyso-thermosensitive liposomal doxorubicin (0)

tirapazamine (0)

dexrazoxane (0)

doxorubicin liposomal (0)

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No biomarker	Non-Hodgkin’s Lymphoma	No biomarker	Non-Hodgkin’s Lymphoma	pixantrone Sensitive: A1 - Approval pixantrone Sensitive : A1	pixantrone Sensitive: A1 - Approval pixantrone Sensitive : A1
MYC positive	Diffuse Large B Cell Lymphoma	MYC positive	Diffuse Large B Cell Lymphoma	pixantrone Sensitive: C3 – Early Trials pixantrone Sensitive : C3	pixantrone Sensitive: C3 – Early Trials pixantrone Sensitive : C3
BCL6 positive	Diffuse Large B Cell Lymphoma	BCL6 positive	Diffuse Large B Cell Lymphoma	pixantrone Sensitive: C3 – Early Trials pixantrone Sensitive : C3	pixantrone Sensitive: C3 – Early Trials pixantrone Sensitive : C3
BCL2 positive	Diffuse Large B Cell Lymphoma	BCL2 positive	Diffuse Large B Cell Lymphoma	pixantrone Sensitive: C3 – Early Trials pixantrone Sensitive : C3	pixantrone Sensitive: C3 – Early Trials pixantrone Sensitive : C3