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DRUG:

VLS-211

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Company:

Merck (MSD)

Drug class:

Topoisomerase II inhibitor, ROR1-targeted antibody-drug conjugate

Related drugs:

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doxorubicin hydrochloride (87)

etoposide IV (53)

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pegylated liposomal doxorubicin (31)

epirubicin (29)

daunorubicin (20)

cytarabine/daunorubicin liposomal formulation (19)

idarubicin hydrochloride (16)

mitoxantrone (16)

dactinomycin (8)

non-pegylated liposomal doxorubicin (3)

pegylated liposomal doxorubicin (1)

zoptarelin doxorubicin (1)

mitoxantrone liposomal (0)

H-ferritin–nanocaged doxorubicin (0)

non-pegylated liposomal doxorubicin (0)

lyso-thermosensitive liposomal doxorubicin (0)

tirapazamine (0)

dexrazoxane (0)

doxorubicin liposomal (0)

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ROR1 expression

Acute Lymphocytic Leukemia

Sensitive: D – Preclinical

Sensitive: D – Preclinical