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DRUG:

LAE005

i
Other names: FAZ053, FAZ 053, FAZ-053, LAE005
Associations
Company:
Laekna Therap, Novartis
Drug class:
PD-L1 inhibitor
Related drugs:
Associations
9ms
A Study of FAZ053 Single Agent and in Combination With PDR001 in Patients With Advanced Malignancies. (clinicaltrials.gov)
P1, N=154, Active, not recruiting, Novartis Pharmaceuticals | Trial completion date: Jun 2024 --> Nov 2024 | Trial primary completion date: Jun 2024 --> Nov 2024
Trial completion date • Trial primary completion date • Combination therapy • Metastases
|
spartalizumab (PDR001) • LAE005
10ms
PhI to Solid Tumors and PhII to Locally Advanced or mTNBC (clinicaltrials.gov)
P1, N=21, Completed, Laekna Limited | Recruiting --> Completed
Trial completion
|
HER-2 (Human epidermal growth factor receptor 2) • PD-L1 (Programmed death ligand 1) • ER (Estrogen receptor) • PGR (Progesterone receptor) • PTEN (Phosphatase and tensin homolog) • BRCA (Breast cancer early onset) • PI3K (Phosphoinositide 3-kinases)
|
PD-L1 expression • PGR expression
|
albumin-bound paclitaxel • afuresertib (LAE002) • LAE005