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DRUG:

retlirafusp alfa (SHR-1701)

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Company:

Dong-A, Jiangsu Hengrui Pharma

Drug class:

PD-L1 inhibitor, TGF-β R2 kinase inhibitor

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PD-L1.t-haNK (0)

PF-07257876 (0)

Undisclosed anti-PD-L1 antibody (0)

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EGFR mutation	Non Small Cell Lung Cancer	EGFR mutation	Non Small Cell Lung Cancer	SHR-1701 Sensitive: C3 – Early Trials SHR-1701 Sensitive : C3	SHR-1701 Sensitive: C3 – Early Trials SHR-1701 Sensitive : C3
PD-L1 overexpression	Gastric Cancer	PD-L1 overexpression	Gastric Cancer	SHR-1701 Sensitive: C3 – Early Trials SHR-1701 Sensitive : C3	SHR-1701 Sensitive: C3 – Early Trials SHR-1701 Sensitive : C3
PD-L1 overexpression	Non Small Cell Lung Cancer	PD-L1 overexpression	Non Small Cell Lung Cancer	SHR-1701 Sensitive: C3 – Early Trials SHR-1701 Sensitive : C3	SHR-1701 Sensitive: C3 – Early Trials SHR-1701 Sensitive : C3
HER-2 negative + PD-L1 expression	Gastroesophageal Junction Adenocarcinoma	HER-2 negative + PD-L1 expression	Gastroesophageal Junction Adenocarcinoma	bevacizumab + SHR-1701 Sensitive: C3 – Early Trials bevacizumab + SHR-1701 Sensitive : C3	bevacizumab + SHR-1701 Sensitive: C3 – Early Trials bevacizumab + SHR-1701 Sensitive : C3
HER-2 negative + PD-L1 expression	Gastric Cancer	HER-2 negative + PD-L1 expression	Gastric Cancer	bevacizumab + SHR-1701 Sensitive: C3 – Early Trials bevacizumab + SHR-1701 Sensitive : C3	bevacizumab + SHR-1701 Sensitive: C3 – Early Trials bevacizumab + SHR-1701 Sensitive : C3
HER-2 negative + PD-L1 expression	Lung Non-Squamous Non-Small Cell Cancer	HER-2 negative + PD-L1 expression	Lung Non-Squamous Non-Small Cell Cancer	bevacizumab + SHR-1701 Sensitive: C3 – Early Trials bevacizumab + SHR-1701 Sensitive : C3	bevacizumab + SHR-1701 Sensitive: C3 – Early Trials bevacizumab + SHR-1701 Sensitive : C3