We also compared the pharmacokinetic profiles of IMMH-010 in rodents and primates. After oral administration of IMMH-010, the general exposure of active metabolite YPD-29B was slightly lower in primates than in rodents, suggesting that data should be extrapolated cautiously from rodents to humans.
over 3 years ago
Journal
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PD-L1 (Programmed death ligand 1) • CES1 (Carboxylesterase 1)