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4years
Inter- and Intratumor Heterogeneity of EGFR Compound Mutations in Non-Small Cell Lung Cancers: Analysis of Five Cases. (PubMed, Clin Lung Cancer)
No intra- or intertumor heterogeneity was observed for EGFR compound mutations. Our results indicate that both EGFR mutations were truncal and selective elimination of cancer cells with uncommon EGFR mutations is unrealistic.
Clinical • Journal
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EGFR (Epidermal growth factor receptor) • TERT (Telomerase Reverse Transcriptase)
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EGFR mutation • EGFR L858R • EGFR G719X • EGFR S768I • EGFR G719A • EGFR G719X + EGFR S768I • EGFR E709G • EGFR G719A + EGFR S768I • EGFR L858R + EGFR R776H • EGFR L858R + EGFR S768I