Journal • Tumor mutational burden • PD(L)-1 Biomarker • IO biomarker • Metastases
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PD-L1 (Programmed death ligand 1) • TP53 (Tumor protein P53) • PIK3CA (Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha) • TMB (Tumor Mutational Burden) • KMT2C (Lysine Methyltransferase 2C)
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TP53 mutation • TMB-H • PIK3CA mutation • MLL mutation • MLL3 mutation
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Focus V (anlotinib) • benmelstobart (APL-502)