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DRUG CLASS:

Telomerase inhibitor

DRUG CLASS:

Telomerase inhibitor

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News alerts, weekly reports and conference planners

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CCL11 overexpression	Pancreatic Ductal Adenocarcinoma	CCL11 overexpression	Pancreatic Ductal Adenocarcinoma	tertomotide Sensitive: B - Late Trials tertomotide Sensitive : B	tertomotide Sensitive: B - Late Trials tertomotide Sensitive : B
MYB underexpression	Adenoid Cystic Carcinoma	MYB underexpression	Adenoid Cystic Carcinoma	tretinoin Sensitive: C3 – Early Trials tretinoin Sensitive : C3	tretinoin Sensitive: C3 – Early Trials tretinoin Sensitive : C3
NOTCH1 mutation	Adenoid Cystic Carcinoma	NOTCH1 mutation	Adenoid Cystic Carcinoma	tretinoin Sensitive: C3 – Early Trials tretinoin Sensitive : C3	tretinoin Sensitive: C3 – Early Trials tretinoin Sensitive : C3
WT1 overexpression	Myelodysplastic Syndrome	WT1 overexpression	Myelodysplastic Syndrome	cytarabine + decitabine + tretinoin Sensitive: C3 – Early Trials cytarabine + decitabine + tretinoin Sensitive : C3	cytarabine + decitabine + tretinoin Sensitive: C3 – Early Trials cytarabine + decitabine + tretinoin Sensitive : C3
TP53 mutation	Myelodysplastic Syndrome	TP53 mutation	Myelodysplastic Syndrome	cytarabine + decitabine + tretinoin Sensitive: C3 – Early Trials cytarabine + decitabine + tretinoin Sensitive : C3	cytarabine + decitabine + tretinoin Sensitive: C3 – Early Trials cytarabine + decitabine + tretinoin Sensitive : C3
ASXL1 mutation	Myelodysplastic Syndrome	ASXL1 mutation	Myelodysplastic Syndrome	cytarabine + decitabine + tretinoin Sensitive: C3 – Early Trials cytarabine + decitabine + tretinoin Sensitive : C3	cytarabine + decitabine + tretinoin Sensitive: C3 – Early Trials cytarabine + decitabine + tretinoin Sensitive : C3
PML-RARA fusion	Acute Promyelocytic Leukemia	PML-RARA fusion	Acute Promyelocytic Leukemia	tretinoin + arsenic trioxide Sensitive: C3 – Early Trials tretinoin + arsenic trioxide Sensitive : C3	tretinoin + arsenic trioxide Sensitive: C3 – Early Trials tretinoin + arsenic trioxide Sensitive : C3
AKT1 overexpression	Glioblastoma	AKT1 overexpression	Glioblastoma	sodium metaarsenite Sensitive: D – Preclinical sodium metaarsenite Sensitive : D	sodium metaarsenite Sensitive: D – Preclinical sodium metaarsenite Sensitive : D
TP53 mutation	Acute Myelogenous Leukemia	TP53 mutation	Acute Myelogenous Leukemia	BIBR1532 Sensitive: D – Preclinical BIBR1532 Sensitive : D	BIBR1532 Sensitive: D – Preclinical BIBR1532 Sensitive : D