^
Association details:
| Biomarker: | PML-RARA fusion |
|---|---|
| Cancer: | Acute Promyelocytic Leukemia |
| Drug: | Vesanoid (tretinoin) (Cytotoxic T lymphocyte stimulant, Telomerase inhibitor, Retinoic acid receptor agonist) + arsenic trioxide (Apoptosis stimulant) |
| Direction: | Sensitive |
Evidence:
Title:
An Outcome Analysis of Childhood Acute Promyelocytic Leukemia Treated with Atra and Arsenic Trioxide, and Limited Dose Anthracycline
Published date:
10/01/2021
Excerpt:
A total of 30 patients with APL...Diagnosis was established on bone marrow aspirate and confirmed by the presence of PML-RARA translocation....The attainment of 100% molecular remission and absence of relapse supports the effectiveness of this regimen.
DOI:
10.1007/s12288-021-01404-1
