Subgroup analysis showed that ORR was 52.0% (95% CI, 31.3-72.2) in the PD-L1 TPS ≥50% population and 37.0% (95% CI, 19.4-57.6) in the <50% population; DCR was 64.0% (95% CI, 42.5-82.0) and 81.5% (95% CI, 61.9-93.7), respectively….SHR-1701 shows encouraging anti-tumor activity in treatment-naive PD-L1+ advanced/metastatic NSCLC pts, compared with the reported historical data of ICI monotherapy. Pts with PD-L1 TPS ≥50% have superior ORR.