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BIOMARKER:
RB1 deletion
i
Other names:
RB1, Retinoblastoma 1, RB Transcriptional Corepressor 1, Protein Phosphatase 1, Regulatory Subunit 130, Prepro-Retinoblastoma-Associated Protein, Retinoblastoma-Associated Protein, Retinoblastoma-Associated Protein, Retinoblastoma Suspectibility Protein
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Entrez ID:
5925
Related biomarkers:
Expression
Mutation
CNA
Others
‹
RB1 expression (7)
MMP17 expression + EGFR expression + RB1 expression (2)
RB1 overexpression (2)
RB1 positive (2)
RB1 negative (1)
RB1 expression (7)
MMP17 expression + EGFR expression + RB1 expression (2)
RB1 overexpression (2)
RB1 positive (2)
RB1 negative (1)
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RB1 deletion
Prostate Cancer
RB1 deletion
Prostate Cancer
abiraterone acetate
Resistant: B - Late Trials
abiraterone acetate
Resistant
:
B
abiraterone acetate
Resistant: B - Late Trials
abiraterone acetate
Resistant
:
B
RB1 deletion
Prostate Cancer
RB1 deletion
Prostate Cancer
enzalutamide
Resistant: B - Late Trials
enzalutamide
Resistant
:
B
enzalutamide
Resistant: B - Late Trials
enzalutamide
Resistant
:
B
RB1 deletion
Hormone Receptor Positive Breast Cancer
RB1 deletion
Hormone Receptor Positive Breast Cancer
palbociclib
Resistant: C3 – Early Trials
palbociclib
Resistant
:
C3
palbociclib
Resistant: C3 – Early Trials
palbociclib
Resistant
:
C3
RB1 deletion
Melanoma
RB1 deletion
Melanoma
palbociclib
Resistant: D – Preclinical
palbociclib
Resistant
:
D
palbociclib
Resistant: D – Preclinical
palbociclib
Resistant
:
D
RB1 deletion
Mesothelioma
RB1 deletion
Mesothelioma
NBL-001
Sensitive: D – Preclinical
NBL-001
Sensitive
:
D
NBL-001
Sensitive: D – Preclinical
NBL-001
Sensitive
:
D
RB1 deletion
Mesothelioma
RB1 deletion
Mesothelioma
MLN8237
Sensitive: D – Preclinical
MLN8237
Sensitive
:
D
MLN8237
Sensitive: D – Preclinical
MLN8237
Sensitive
:
D
RB1 deletion
Mantle Cell Lymphoma
RB1 deletion
Mantle Cell Lymphoma
palbociclib
Sensitive: D – Preclinical
palbociclib
Sensitive
:
D
palbociclib
Sensitive: D – Preclinical
palbociclib
Sensitive
:
D
RB1 deletion
Ovarian Cancer
RB1 deletion
Ovarian Cancer
SRA515
Sensitive: D – Preclinical
SRA515
Sensitive
:
D
SRA515
Sensitive: D – Preclinical
SRA515
Sensitive
:
D
RB1 deletion
Ovarian Cancer
RB1 deletion
Ovarian Cancer
palbociclib + SRA515
Sensitive: D – Preclinical
palbociclib + SRA515
Sensitive
:
D
palbociclib + SRA515
Sensitive: D – Preclinical
palbociclib + SRA515
Sensitive
:
D
RB1 deletion
Estrogen Receptor Positive Breast Cancer
RB1 deletion
Estrogen Receptor Positive Breast Cancer
IGM-9427
Sensitive: D – Preclinical
IGM-9427
Sensitive
:
D
IGM-9427
Sensitive: D – Preclinical
IGM-9427
Sensitive
:
D
RB1 deletion
Estrogen Receptor Positive Breast Cancer
RB1 deletion
Estrogen Receptor Positive Breast Cancer
WEE1 inhibitor + Aurora kinase inhibitor
Sensitive: D – Preclinical
WEE1 inhibitor + Aurora kinase inhibitor
Sensitive
:
D
WEE1 inhibitor + Aurora kinase inhibitor
Sensitive: D – Preclinical
WEE1 inhibitor + Aurora kinase inhibitor
Sensitive
:
D
RB1 deletion
Estrogen Receptor Positive Breast Cancer
RB1 deletion
Estrogen Receptor Positive Breast Cancer
GSK3326595
Sensitive: D – Preclinical
GSK3326595
Sensitive
:
D
GSK3326595
Sensitive: D – Preclinical
GSK3326595
Sensitive
:
D
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