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BIOMARKER:
PTEN deletion
i
Other names: PTEN, Phosphatase and tensin homolog, Mutated In Multiple Advanced Cancers 1, Phosphatase And Tensin Homolog, Phosphatidylinositol 3,4,5-Trisphosphate 3-Phosphatase And Dual-Specificity Protein Phosphatase PTEN, MMAC1, TEP1, MMAC1 Phosphatase And Tensin Homolog Deleted On Chromosome 10, Mitochondrial Phosphatase And Tensin Protein Alpha, Phosphatase And Tensin-Like Protein, Protein Tyrosine Phosphatase, Mitochondrial PTENalpha, PTENbeta, PTEN1, CWS1, GLM2, MHAM
Entrez ID:
Related biomarkers:
PTEN deletion
HER2 Positive Breast Cancer
everolimus
Sensitive
:
B
PTEN deletion
Solid Tumor
avelumab
Sensitive
:
C3
PTEN deletion
Gastric Cancer
trastuzumab
Resistant
:
C3
PTEN deletion
Gastric Cancer
lapatinib
Resistant
:
C3
PTEN deletion
CRC
cetuximab
Resistant
:
C3
PTEN deletion
Melanoma
Immunotherapy
Resistant
:
C3
PTEN deletion
Endometrial Cancer
olaparib
Sensitive
:
C3
PTEN deletion
CRC
panitumumab
Resistant
:
C3
PTEN deletion
Prostate Cancer
everolimus
Sensitive
:
C3
PTEN deletion
HER2 Positive Breast Cancer
trastuzumab
Resistant
:
C3
PTEN deletion
Prostate Cancer
abiraterone acetate
Resistant
:
C3
PTEN deletion
Prostate Cancer
enzalutamide
Resistant
:
C3
PTEN deletion
Prostate Cancer
GSK2636771
Sensitive
:
C4
PTEN deletion
Chordoma
PDGFR inhibitor
Resistant
:
C4
PTEN deletion
Chordoma
PDGFR inhibitor + HDAC inhibitor
Sensitive
:
C4
PTEN deletion
Breast Cancer
alpelisib
Resistant
:
C4
PTEN deletion
Melanoma
dabrafenib
Sensitive
:
C4
PTEN deletion
Prostate Cancer
ATM kinase inhibitor
Sensitive
:
D
PTEN deletion
Gastric Cancer
AZD5363
Sensitive
:
D
PTEN deletion
HER2 Positive Breast Cancer
MEN1611
Sensitive
:
D
PTEN deletion
GBM
MLN4924
Resistant
:
D
PTEN deletion
Glioma
MLN4924
Resistant
:
D
PTEN deletion
Ovarian Cancer
CERC-006
Sensitive
:
D
PTEN deletion
Ovarian Cancer
PD-0325901 + PF-04691502
Sensitive
:
D
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