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BIOMARKER:

PTEN deletion

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Other names: PTEN, Phosphatase and tensin homolog, Mutated In Multiple Advanced Cancers 1, Phosphatase And Tensin Homolog, Phosphatidylinositol 3,4,5-Trisphosphate 3-Phosphatase And Dual-Specificity Protein Phosphatase PTEN, MMAC1, TEP1, MMAC1 Phosphatase And Tensin Homolog Deleted On Chromosome 10, Mitochondrial Phosphatase And Tensin Protein Alpha, Phosphatase And Tensin-Like Protein, Protein Tyrosine Phosphatase, Mitochondrial PTENalpha, PTENbeta, PTEN1, CWS1, GLM2, MHAM
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Entrez ID:
Related biomarkers:
PTEN deletion
Prostate Cancer
RG7440
Sensitive
:
B
PTEN deletion
HER2 Positive Breast Cancer
everolimus
Sensitive
:
B
PTEN deletion
Solid Tumor
avelumab
Sensitive
:
C3
PTEN deletion
Gastric Cancer
trastuzumab
Resistant
:
C3
PTEN deletion
Gastric Cancer
lapatinib
Resistant
:
C3
PTEN deletion
Breast Cancer
bevacizumab + temsirolimus
Sensitive
:
C3
PTEN deletion
Prostate Cancer
GSK2636771
Sensitive
:
C3
PTEN deletion
Colorectal Cancer
cetuximab
Resistant
:
C3
PTEN deletion
Melanoma
Immunotherapy
Resistant
:
C3
PTEN deletion
Melanoma
vemurafenib
Sensitive
:
C3
PTEN deletion
Endometrial Cancer
olaparib
Sensitive
:
C3
PTEN deletion
Colorectal Cancer
panitumumab
Resistant
:
C3
PTEN deletion
Colorectal Cancer
bevacizumab + nanoparticle albumin-bound rapamycin
Sensitive
:
C3
PTEN deletion
Prostate Cancer
everolimus
Sensitive
:
C3
PTEN deletion
HER2 Positive Breast Cancer
trastuzumab
Resistant
:
C3
PTEN deletion
Prostate Cancer
abiraterone acetate
Resistant
:
C3
PTEN deletion
Prostate Cancer
enzalutamide capsule
Resistant
:
C3
PTEN deletion
Prostate Cancer
darolutamide
Sensitive
:
C3
PTEN deletion
Prostate Cancer
apalutamide
Sensitive
:
C3
PTEN deletion
Prostate Cancer
enzalutamide capsule + CC-115
Sensitive
:
C3
PTEN deletion
Renal Cell Carcinoma
CB-228
Resistant
:
C3
PTEN deletion
Prostate Cancer
pembrolizumab + GSK2636771
Sensitive
:
C3
PTEN deletion
Chordoma
PDGFR inhibitor
Resistant
:
C4
PTEN deletion
Chordoma
PDGFR inhibitor + HDAC inhibitor
Sensitive
:
C4
PTEN deletion
Breast Cancer
alpelisib
Resistant
:
C4
PTEN deletion
Melanoma
dabrafenib
Sensitive
:
C4
PTEN deletion
Prostate Cancer
ATM kinase inhibitor
Sensitive
:
D
PTEN deletion
Gastric Cancer
AZD5363
Sensitive
:
D
PTEN deletion
Triple Negative Breast Cancer
AZD8186
Sensitive
:
D
PTEN deletion
HER2 Positive Breast Cancer
MEN1611
Sensitive
:
D
PTEN deletion
Glioblastoma
MLN4924
Resistant
:
D
PTEN deletion
Glioma
MLN4924
Resistant
:
D