GNA11 Q209L	Uveal Melanoma	GNA11 Q209L	Uveal Melanoma	IDE196 Sensitive: C3 – Early Trials IDE196 Sensitive : C3	IDE196 Sensitive: C3 – Early Trials IDE196 Sensitive : C3
GNAQ mutation	Uveal Melanoma	GNAQ mutation	Uveal Melanoma	AEB071 Sensitive: C3 – Early Trials AEB071 Sensitive : C3	AEB071 Sensitive: C3 – Early Trials AEB071 Sensitive : C3
GNA11 mutation	Uveal Melanoma	GNA11 mutation	Uveal Melanoma	AEB071 Sensitive: C3 – Early Trials AEB071 Sensitive : C3	AEB071 Sensitive: C3 – Early Trials AEB071 Sensitive : C3
PRKCH-SPTB fusion	Cutaneous Melanoma	PRKCH-SPTB fusion	Cutaneous Melanoma	IDE196 Sensitive: D – Preclinical IDE196 Sensitive : D	IDE196 Sensitive: D – Preclinical IDE196 Sensitive : D
PRKCH fusion	Cutaneous Melanoma	PRKCH fusion	Cutaneous Melanoma	IDE196 Sensitive: D – Preclinical IDE196 Sensitive : D	IDE196 Sensitive: D – Preclinical IDE196 Sensitive : D
PRKCH fusion	Colorectal Cancer	PRKCH fusion	Colorectal Cancer	IDE196 Resistant: D – Preclinical IDE196 Resistant : D	IDE196 Resistant: D – Preclinical IDE196 Resistant : D
PRKCH-SPTB fusion	Colorectal Cancer	PRKCH-SPTB fusion	Colorectal Cancer	IDE196 Sensitive: D – Preclinical IDE196 Sensitive : D	IDE196 Sensitive: D – Preclinical IDE196 Sensitive : D
PRKCH-VWA2 fusion	Colorectal Cancer	PRKCH-VWA2 fusion	Colorectal Cancer	IDE196 Sensitive: D – Preclinical IDE196 Sensitive : D	IDE196 Sensitive: D – Preclinical IDE196 Sensitive : D
HIF1A-PRKCH fusion	Colorectal Cancer	HIF1A-PRKCH fusion	Colorectal Cancer	IDE196 Sensitive: D – Preclinical IDE196 Sensitive : D	IDE196 Sensitive: D – Preclinical IDE196 Sensitive : D
HIF1A-PRKCH fusion	Cutaneous Melanoma	HIF1A-PRKCH fusion	Cutaneous Melanoma	IDE196 Resistant: D – Preclinical IDE196 Resistant : D	IDE196 Resistant: D – Preclinical IDE196 Resistant : D
PRKCH-VWA2 fusion	Cutaneous Melanoma	PRKCH-VWA2 fusion	Cutaneous Melanoma	IDE196 Sensitive: D – Preclinical IDE196 Sensitive : D	IDE196 Sensitive: D – Preclinical IDE196 Sensitive : D
NF1 470G>T	Glioblastoma	NF1 470G>T	Glioblastoma	RO-31-8220 Sensitive: D – Preclinical RO-31-8220 Sensitive : D	RO-31-8220 Sensitive: D – Preclinical RO-31-8220 Sensitive : D

PKC inhibitor

PKC inhibitor

Associations(29)

Associations
(29)