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BIOMARKER:
PD-L1 elevation
i
Other names:
PD-L1, CD274, HPD-L1, PD-L1, B7H1, PDL1, Programmed death ligand 1, B7-H1, B7-H, PDCD1L1, PDCD1LG1, PDCD1 Ligand 1, B7 homolog 1, CD274 Antigen, Programmed cell death 1 ligand 1, CD274 molecule
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Entrez ID:
29126
Related biomarkers:
Expression
Mutation
CNA
Others
‹
PD-L1 expression (356)
PD-L1 overexpression (181)
PD-L1 underexpression (46)
PD-L1 negative (28)
HER-2 negative + PD-L1 expression (12)
HER-2 positive + PD-L1 expression (3)
HR negative + PD-L1 expression (2)
MSLN overexpression + PD-L1 overexpression (2)
PD-L1 expression + CD68 positive (2)
PD-L1 expression + HER-2 overexpression (2)
PD-L1 expression + PVR expression (2)
PD-L1 overexpression + CD8 overexpression (2)
TTF1 expression + PD-L1 expression (2)
miR-625-5p underexpression + PD-L1 overexpression (2)
AXL overexpression + PD-L1 expression (1)
CGAS overexpression + PD-L1 overexpression (1)
CMTM4 expression + PD-L1 expression (1)
CMTM6 expression + PD-L1 expression (1)
CMTM6 overexpression + PD-L1 overexpression (1)
CXCL12 expression + PD-L1 underexpression (1)
HLA-A underexpression + PD-L1 expression (1)
HR positive + PD-L1 expression (1)
IGFBP2 overexpression + PD-L1 overexpression (1)
MHC-II overexpression + PD-L1 negative (1)
MHC-II overexpression + PD-L1 underexpression (1)
NKX2-1 expression + PD-L1 expression (1)
NR1H4 overexpression + PD‑L1 underexpression (1)
NT5E overexpression + PD-L1 expression (1)
PD-1 underexpression + PD-L1 overexpression (1)
PD-L1 expression + CD14 positive (1)
PD-L1 expression + CD47 expression (1)
PD-L1 expression + CD8 negative + GZMB negative (1)
PD-L1 expression + CD8 positive (1)
PD-L1 expression + CTLA4 expression (1)
PD-L1 expression + MTOR overexpression (1)
PD-L1 expression + REV3L overexpression (1)
PD-L1 overexpression + APOBEC3B overexpression (1)
PD-L1 overexpression + CCL5 overexpression (1)
PD-L1 overexpression + CD163 underexpression (1)
PD-L1 overexpression + ER positive (1)
PD-L1 overexpression + GZMA overexpression (1)
PD-L1 overexpression + LAG3 expression + CTAG1B expression (1)
PD-L1 overexpression + PD-L2 underexpression (1)
PD-L1 overexpression + SOX2 overexpression (1)
RBM17 expression + PD-L1 expression (1)
RET positive + PD-L1 overexpression (1)
SNX20 overexpression + PD-L1 overexpression (1)
STK11 underexpression + PD-L1 overexpression (1)
TFRC overexpression + PD-L1 underexpression (1)
TNFSF4 overexpression + PD-L1 overexpression (1)
TTF1 expression + PD-L1 overexpression (1)
HER-2 negative + HR negative + PD-L1 expression (0)
PD-L1 expression + HER-2 expression (0)
PD-L1 expression + LAG3 expression (0)
PD-L1 expression + TTF1 expression (0)
TMB + PD-L1 expression (0)
PD-L1 expression (356)
PD-L1 overexpression (181)
PD-L1 underexpression (46)
PD-L1 negative (28)
HER-2 negative + PD-L1 expression (12)
HER-2 positive + PD-L1 expression (3)
HR negative + PD-L1 expression (2)
MSLN overexpression + PD-L1 overexpression (2)
PD-L1 expression + CD68 positive (2)
PD-L1 expression + HER-2 overexpression (2)
PD-L1 expression + PVR expression (2)
PD-L1 overexpression + CD8 overexpression (2)
TTF1 expression + PD-L1 expression (2)
miR-625-5p underexpression + PD-L1 overexpression (2)
AXL overexpression + PD-L1 expression (1)
CGAS overexpression + PD-L1 overexpression (1)
CMTM4 expression + PD-L1 expression (1)
CMTM6 expression + PD-L1 expression (1)
CMTM6 overexpression + PD-L1 overexpression (1)
CXCL12 expression + PD-L1 underexpression (1)
HLA-A underexpression + PD-L1 expression (1)
HR positive + PD-L1 expression (1)
IGFBP2 overexpression + PD-L1 overexpression (1)
MHC-II overexpression + PD-L1 negative (1)
MHC-II overexpression + PD-L1 underexpression (1)
NKX2-1 expression + PD-L1 expression (1)
NR1H4 overexpression + PD‑L1 underexpression (1)
NT5E overexpression + PD-L1 expression (1)
PD-1 underexpression + PD-L1 overexpression (1)
PD-L1 expression + CD14 positive (1)
PD-L1 expression + CD47 expression (1)
PD-L1 expression + CD8 negative + GZMB negative (1)
PD-L1 expression + CD8 positive (1)
PD-L1 expression + CTLA4 expression (1)
PD-L1 expression + MTOR overexpression (1)
PD-L1 expression + REV3L overexpression (1)
PD-L1 overexpression + APOBEC3B overexpression (1)
PD-L1 overexpression + CCL5 overexpression (1)
PD-L1 overexpression + CD163 underexpression (1)
PD-L1 overexpression + ER positive (1)
PD-L1 overexpression + GZMA overexpression (1)
PD-L1 overexpression + LAG3 expression + CTAG1B expression (1)
PD-L1 overexpression + PD-L2 underexpression (1)
PD-L1 overexpression + SOX2 overexpression (1)
RBM17 expression + PD-L1 expression (1)
RET positive + PD-L1 overexpression (1)
SNX20 overexpression + PD-L1 overexpression (1)
STK11 underexpression + PD-L1 overexpression (1)
TFRC overexpression + PD-L1 underexpression (1)
TNFSF4 overexpression + PD-L1 overexpression (1)
TTF1 expression + PD-L1 overexpression (1)
HER-2 negative + HR negative + PD-L1 expression (0)
PD-L1 expression + HER-2 expression (0)
PD-L1 expression + LAG3 expression (0)
PD-L1 expression + TTF1 expression (0)
TMB + PD-L1 expression (0)
›
Associations
News
Trials
VERI cancer hierarchy
Reset Filters
PD-L1 elevation
HER2 Positive Breast Cancer
PD-L1 elevation
HER2 Positive Breast Cancer
trastuzumab
Resistant: B - Late Trials
trastuzumab
Resistant
:
B
trastuzumab
Resistant: B - Late Trials
trastuzumab
Resistant
:
B
PD-L1 elevation
Non-Hodgkin’s Lymphoma
PD-L1 elevation
Non-Hodgkin’s Lymphoma
Resistant: C3 – Early Trials
Resistant
:
C3
Resistant: C3 – Early Trials
Resistant
:
C3
PD-L1 elevation
Urothelial Cancer
PD-L1 elevation
Urothelial Cancer
atezolizumab
Sensitive: C3 – Early Trials
atezolizumab
Sensitive
:
C3
atezolizumab
Sensitive: C3 – Early Trials
atezolizumab
Sensitive
:
C3
PD-L1 elevation
Non Small Cell Lung Cancer
PD-L1 elevation
Non Small Cell Lung Cancer
nivolumab
Resistant: C3 – Early Trials
nivolumab
Resistant
:
C3
nivolumab
Resistant: C3 – Early Trials
nivolumab
Resistant
:
C3
PD-L1 elevation
Non Small Cell Lung Cancer
PD-L1 elevation
Non Small Cell Lung Cancer
pembrolizumab
Resistant: C3 – Early Trials
pembrolizumab
Resistant
:
C3
pembrolizumab
Resistant: C3 – Early Trials
pembrolizumab
Resistant
:
C3
PD-L1 elevation
Non Small Cell Lung Cancer
PD-L1 elevation
Non Small Cell Lung Cancer
Immunotherapy
Resistant: C3 – Early Trials
Immunotherapy
Resistant
:
C3
Immunotherapy
Resistant: C3 – Early Trials
Immunotherapy
Resistant
:
C3
PD-L1 elevation
Bladder Cancer
PD-L1 elevation
Bladder Cancer
Immunotherapy
Resistant: C3 – Early Trials
Immunotherapy
Resistant
:
C3
Immunotherapy
Resistant: C3 – Early Trials
Immunotherapy
Resistant
:
C3
PD-L1 elevation
Neuroendocrine Tumor
PD-L1 elevation
Neuroendocrine Tumor
everolimus
Resistant: C3 – Early Trials
everolimus
Resistant
:
C3
everolimus
Resistant: C3 – Early Trials
everolimus
Resistant
:
C3
PD-L1 elevation
Colorectal Cancer
PD-L1 elevation
Colorectal Cancer
durvalumab + tremelimumab
Resistant: C3 – Early Trials
durvalumab + tremelimumab
Resistant
:
C3
durvalumab + tremelimumab
Resistant: C3 – Early Trials
durvalumab + tremelimumab
Resistant
:
C3
PD-L1 elevation
Solid Tumor
PD-L1 elevation
Solid Tumor
Immunotherapy
Resistant: C3 – Early Trials
Immunotherapy
Resistant
:
C3
Immunotherapy
Resistant: C3 – Early Trials
Immunotherapy
Resistant
:
C3
PD-L1 elevation
Urothelial Cancer
PD-L1 elevation
Urothelial Cancer
Immunotherapy
Resistant: C3 – Early Trials
Immunotherapy
Resistant
:
C3
Immunotherapy
Resistant: C3 – Early Trials
Immunotherapy
Resistant
:
C3
PD-L1 elevation
Small Cell Lung Cancer
PD-L1 elevation
Small Cell Lung Cancer
Immunotherapy
Resistant: C3 – Early Trials
Immunotherapy
Resistant
:
C3
Immunotherapy
Resistant: C3 – Early Trials
Immunotherapy
Resistant
:
C3
PD-L1 elevation
Melanoma
PD-L1 elevation
Melanoma
Immunotherapy
Resistant: C3 – Early Trials
Immunotherapy
Resistant
:
C3
Immunotherapy
Resistant: C3 – Early Trials
Immunotherapy
Resistant
:
C3
PD-L1 elevation
Lung Cancer
PD-L1 elevation
Lung Cancer
Immunotherapy
Resistant: C3 – Early Trials
Immunotherapy
Resistant
:
C3
Immunotherapy
Resistant: C3 – Early Trials
Immunotherapy
Resistant
:
C3
PD-L1 elevation
Non Small Cell Lung Cancer
PD-L1 elevation
Non Small Cell Lung Cancer
trametinib
Sensitive: D – Preclinical
trametinib
Sensitive
:
D
trametinib
Sensitive: D – Preclinical
trametinib
Sensitive
:
D
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