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Association details:
Biomarker:
PD-L1 elevation
Cancer:
HER2 Positive Breast Cancer
Drug:
Herceptin (trastuzumab)
(
HER2 inhibitor
)
Direction:
Resistant
Evidence:
Evidence Level:
Resistant: B - Late Trials
Source:
Cancer
Title:
Higher serum PD-L1 level predicts increased overall survival with lapatinib versus trastuzumab in the CCTG MA.31 phase 3 trial
Published date:
09/10/2020
Excerpt:
...within the trastuzumab arm, a higher continuous pretreatment serum PD‐L1 level was significant for shorter OS (hazard ratio [HR], 3.85; P = .04)...
DOI:
10.1002/cncr.33149
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