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BIOMARKER:
MLH1 mutation
i
Other names:
MLH1, COCA2, FCC2, HNPCC, HNPCC2, MutL homolog 1
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Entrez ID:
4292
Related biomarkers:
Mutation
CNA
Others
‹
MLH1 V384D (3)
PMS2 mutation + MLH1 mutation (3)
MLH1 V384D (3)
PMS2 mutation + MLH1 mutation (3)
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Associations
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Trials
VERI cancer hierarchy
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MLH1 mutation
Gastric Cancer
MLH1 mutation
Gastric Cancer
tremelimumab
Sensitive: C2 – Inclusion Criteria
tremelimumab
Sensitive
:
C2
tremelimumab
Sensitive: C2 – Inclusion Criteria
tremelimumab
Sensitive
:
C2
MLH1 mutation
Gastric Cancer
MLH1 mutation
Gastric Cancer
durvalumab + tremelimumab
Sensitive: C2 – Inclusion Criteria
durvalumab + tremelimumab
Sensitive
:
C2
durvalumab + tremelimumab
Sensitive: C2 – Inclusion Criteria
durvalumab + tremelimumab
Sensitive
:
C2
MLH1 mutation
Prostate Cancer
MLH1 mutation
Prostate Cancer
olaparib
Sensitive: C2 – Inclusion Criteria
olaparib
Sensitive
:
C2
olaparib
Sensitive: C2 – Inclusion Criteria
olaparib
Sensitive
:
C2
MLH1 mutation
HER2 Positive Breast Cancer
MLH1 mutation
HER2 Positive Breast Cancer
trastuzumab
Resistant: C3 – Early Trials
trastuzumab
Resistant
:
C3
trastuzumab
Resistant: C3 – Early Trials
trastuzumab
Resistant
:
C3
MLH1 mutation
Urothelial Cancer
MLH1 mutation
Urothelial Cancer
pembrolizumab
Sensitive: C4 – Case Studies
pembrolizumab
Sensitive
:
C4
pembrolizumab
Sensitive: C4 – Case Studies
pembrolizumab
Sensitive
:
C4
MLH1 mutation
Urothelial Cancer
MLH1 mutation
Urothelial Cancer
nivolumab + ipilimumab
Sensitive: C4 – Case Studies
nivolumab + ipilimumab
Sensitive
:
C4
nivolumab + ipilimumab
Sensitive: C4 – Case Studies
nivolumab + ipilimumab
Sensitive
:
C4
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