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BIOMARKER:

MLH1 mutation

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MLH1 mutation	Gastric Cancer	MLH1 mutation	Gastric Cancer	tremelimumab Sensitive: C2 – Inclusion Criteria tremelimumab Sensitive : C2	tremelimumab Sensitive: C2 – Inclusion Criteria tremelimumab Sensitive : C2
MLH1 mutation	Gastric Cancer	MLH1 mutation	Gastric Cancer	durvalumab + tremelimumab Sensitive: C2 – Inclusion Criteria durvalumab + tremelimumab Sensitive : C2	durvalumab + tremelimumab Sensitive: C2 – Inclusion Criteria durvalumab + tremelimumab Sensitive : C2
MLH1 mutation	Prostate Cancer	MLH1 mutation	Prostate Cancer	olaparib Sensitive: C2 – Inclusion Criteria olaparib Sensitive : C2	olaparib Sensitive: C2 – Inclusion Criteria olaparib Sensitive : C2
MLH1 mutation	HER2 Positive Breast Cancer	MLH1 mutation	HER2 Positive Breast Cancer	trastuzumab Resistant: C3 – Early Trials trastuzumab Resistant : C3	trastuzumab Resistant: C3 – Early Trials trastuzumab Resistant : C3
MLH1 mutation	Urothelial Cancer	MLH1 mutation	Urothelial Cancer	pembrolizumab Sensitive: C4 – Case Studies pembrolizumab Sensitive : C4	pembrolizumab Sensitive: C4 – Case Studies pembrolizumab Sensitive : C4
MLH1 mutation	Urothelial Cancer	MLH1 mutation	Urothelial Cancer	nivolumab + ipilimumab Sensitive: C4 – Case Studies nivolumab + ipilimumab Sensitive : C4	nivolumab + ipilimumab Sensitive: C4 – Case Studies nivolumab + ipilimumab Sensitive : C4