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BIOMARKER:
KRAS G12C
i
Other names:
KRAS, KRAS1, KRAS2, Kirsten rat sarcoma viral oncogene homolog
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Entrez ID:
3845
Related biomarkers:
Expression
Mutation
CNA
Others
‹
KRAS amplification (7)
KRAS deletion (1)
KRAS amplification (7)
KRAS deletion (1)
›
Related tests:
Guardant360® CDx (54)
therascreen® KRAS RGQ PCR Kit (5)
Resolution ctDx FIRST Assay (1)
Guardant360® CDx (54)
therascreen® KRAS RGQ PCR Kit (5)
Resolution ctDx FIRST Assay (1)
Associations
News
Trials
VERI cancer hierarchy
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KRAS G12C
Non Small Cell Lung Cancer
KRAS G12C
Non Small Cell Lung Cancer
sotorasib
Sensitive: A1 - Approval
sotorasib
Sensitive
:
A1
sotorasib
Sensitive: A1 - Approval
sotorasib
Sensitive
:
A1
KRAS G12C
Non Small Cell Lung Cancer
KRAS G12C
Non Small Cell Lung Cancer
adagrasib
Sensitive: A1 - Approval
adagrasib
Sensitive
:
A1
adagrasib
Sensitive: A1 - Approval
adagrasib
Sensitive
:
A1
KRAS G12C
Colorectal Cancer
KRAS G12C
Colorectal Cancer
adagrasib
Sensitive: A1 - Approval
adagrasib
Sensitive
:
A1
adagrasib
Sensitive: A1 - Approval
adagrasib
Sensitive
:
A1
KRAS G12C
Colorectal Cancer
KRAS G12C
Colorectal Cancer
cetuximab + adagrasib
Sensitive: A1 - Approval
cetuximab + adagrasib
Sensitive
:
A1
cetuximab + adagrasib
Sensitive: A1 - Approval
cetuximab + adagrasib
Sensitive
:
A1
KRAS G12C
Ampulla of Vater Carcinoma
KRAS G12C
Ampulla of Vater Carcinoma
sotorasib
Sensitive: A2 - Guideline
sotorasib
Sensitive
:
A2
sotorasib
Sensitive: A2 - Guideline
sotorasib
Sensitive
:
A2
KRAS G12C
Pancreatic Adenocarcinoma
KRAS G12C
Pancreatic Adenocarcinoma
sotorasib
Sensitive: A2 - Guideline
sotorasib
Sensitive
:
A2
sotorasib
Sensitive: A2 - Guideline
sotorasib
Sensitive
:
A2
KRAS G12C
Pancreatic Adenocarcinoma
KRAS G12C
Pancreatic Adenocarcinoma
adagrasib
Sensitive: A2 - Guideline
adagrasib
Sensitive
:
A2
adagrasib
Sensitive: A2 - Guideline
adagrasib
Sensitive
:
A2
KRAS G12C
Rectal Cancer
KRAS G12C
Rectal Cancer
panitumumab + sotorasib
Sensitive: A2 - Guideline
panitumumab + sotorasib
Sensitive
:
A2
panitumumab + sotorasib
Sensitive: A2 - Guideline
panitumumab + sotorasib
Sensitive
:
A2
KRAS G12C
Rectal Cancer
KRAS G12C
Rectal Cancer
cetuximab + sotorasib
Sensitive: A2 - Guideline
cetuximab + sotorasib
Sensitive
:
A2
cetuximab + sotorasib
Sensitive: A2 - Guideline
cetuximab + sotorasib
Sensitive
:
A2
KRAS G12C
Rectal Cancer
KRAS G12C
Rectal Cancer
panitumumab + adagrasib
Sensitive: A2 - Guideline
panitumumab + adagrasib
Sensitive
:
A2
panitumumab + adagrasib
Sensitive: A2 - Guideline
panitumumab + adagrasib
Sensitive
:
A2
KRAS G12C
Rectal Cancer
KRAS G12C
Rectal Cancer
cetuximab + adagrasib
Sensitive: A2 - Guideline
cetuximab + adagrasib
Sensitive
:
A2
cetuximab + adagrasib
Sensitive: A2 - Guideline
cetuximab + adagrasib
Sensitive
:
A2
KRAS G12C
Colon Cancer
KRAS G12C
Colon Cancer
panitumumab + sotorasib
Sensitive: A2 - Guideline
panitumumab + sotorasib
Sensitive
:
A2
panitumumab + sotorasib
Sensitive: A2 - Guideline
panitumumab + sotorasib
Sensitive
:
A2
KRAS G12C
Colon Cancer
KRAS G12C
Colon Cancer
cetuximab + sotorasib
Sensitive: A2 - Guideline
cetuximab + sotorasib
Sensitive
:
A2
cetuximab + sotorasib
Sensitive: A2 - Guideline
cetuximab + sotorasib
Sensitive
:
A2
KRAS G12C
Colon Cancer
KRAS G12C
Colon Cancer
cetuximab + adagrasib
Sensitive: A2 - Guideline
cetuximab + adagrasib
Sensitive
:
A2
cetuximab + adagrasib
Sensitive: A2 - Guideline
cetuximab + adagrasib
Sensitive
:
A2
KRAS G12C
Colon Cancer
KRAS G12C
Colon Cancer
panitumumab + adagrasib
Sensitive: A2 - Guideline
panitumumab + adagrasib
Sensitive
:
A2
panitumumab + adagrasib
Sensitive: A2 - Guideline
panitumumab + adagrasib
Sensitive
:
A2
KRAS G12C
Ampulla of Vater Carcinoma
KRAS G12C
Ampulla of Vater Carcinoma
adagrasib
Sensitive: A2 - Guideline
adagrasib
Sensitive
:
A2
adagrasib
Sensitive: A2 - Guideline
adagrasib
Sensitive
:
A2
KRAS G12C
Non Small Cell Lung Cancer
KRAS G12C
Non Small Cell Lung Cancer
Immunotherapy
Sensitive: B - Late Trials
Immunotherapy
Sensitive
:
B
Immunotherapy
Sensitive: B - Late Trials
Immunotherapy
Sensitive
:
B
KRAS G12C
Lung Non-Squamous Non-Small Cell Cancer
KRAS G12C
Lung Non-Squamous Non-Small Cell Cancer
Immunotherapy
Sensitive: B - Late Trials
Immunotherapy
Sensitive
:
B
Immunotherapy
Sensitive: B - Late Trials
Immunotherapy
Sensitive
:
B
KRAS G12C
Non Small Cell Lung Cancer
KRAS G12C
Non Small Cell Lung Cancer
abemaciclib
Sensitive: B - Late Trials
abemaciclib
Sensitive
:
B
abemaciclib
Sensitive: B - Late Trials
abemaciclib
Sensitive
:
B
KRAS G12C
Non Small Cell Lung Cancer
KRAS G12C
Non Small Cell Lung Cancer
pembrolizumab
Sensitive: B - Late Trials
pembrolizumab
Sensitive
:
B
pembrolizumab
Sensitive: B - Late Trials
pembrolizumab
Sensitive
:
B
KRAS G12C
Colorectal Cancer
KRAS G12C
Colorectal Cancer
cetuximab
Resistant: B - Late Trials
cetuximab
Resistant
:
B
cetuximab
Resistant: B - Late Trials
cetuximab
Resistant
:
B
KRAS G12C
Colorectal Cancer
KRAS G12C
Colorectal Cancer
panitumumab
Resistant: B - Late Trials
panitumumab
Resistant
:
B
panitumumab
Resistant: B - Late Trials
panitumumab
Resistant
:
B
KRAS G12C
Colorectal Cancer
KRAS G12C
Colorectal Cancer
panitumumab + sotorasib
Sensitive: B - Late Trials
panitumumab + sotorasib
Sensitive
:
B
panitumumab + sotorasib
Sensitive: B - Late Trials
panitumumab + sotorasib
Sensitive
:
B
KRAS G12C
Non Small Cell Lung Cancer
KRAS G12C
Non Small Cell Lung Cancer
sotorasib + BMS-986466
Sensitive: B - Late Trials
sotorasib + BMS-986466
Sensitive
:
B
sotorasib + BMS-986466
Sensitive: B - Late Trials
sotorasib + BMS-986466
Sensitive
:
B
KRAS G12C
Pancreatic Cancer
KRAS G12C
Pancreatic Cancer
JAB-21822
Sensitive: B - Late Trials
JAB-21822
Sensitive
:
B
JAB-21822
Sensitive: B - Late Trials
JAB-21822
Sensitive
:
B
KRAS G12C
Pancreatic Cancer
KRAS G12C
Pancreatic Cancer
sotorasib
Sensitive: C1 - Off-label
sotorasib
Sensitive
:
C1
sotorasib
Sensitive: C1 - Off-label
sotorasib
Sensitive
:
C1
KRAS G12C
Cholangiocarcinoma
KRAS G12C
Cholangiocarcinoma
adagrasib
Sensitive: C1 - Off-label
adagrasib
Sensitive
:
C1
adagrasib
Sensitive: C1 - Off-label
adagrasib
Sensitive
:
C1
KRAS G12C
Ovarian Cancer
KRAS G12C
Ovarian Cancer
adagrasib
Sensitive: C1 - Off-label
adagrasib
Sensitive
:
C1
adagrasib
Sensitive: C1 - Off-label
adagrasib
Sensitive
:
C1
KRAS G12C
Pancreatic Cancer
KRAS G12C
Pancreatic Cancer
adagrasib
Sensitive: C1 - Off-label
adagrasib
Sensitive
:
C1
adagrasib
Sensitive: C1 - Off-label
adagrasib
Sensitive
:
C1
KRAS G12C
Endometrial Cancer
KRAS G12C
Endometrial Cancer
adagrasib
Sensitive: C1 - Off-label
adagrasib
Sensitive
:
C1
adagrasib
Sensitive: C1 - Off-label
adagrasib
Sensitive
:
C1
KRAS G12C
Melanoma
KRAS G12C
Melanoma
sotorasib
Sensitive: C1 - Off-label
sotorasib
Sensitive
:
C1
sotorasib
Sensitive: C1 - Off-label
sotorasib
Sensitive
:
C1
KRAS G12C
Endometrial Cancer
KRAS G12C
Endometrial Cancer
sotorasib
Sensitive: C1 - Off-label
sotorasib
Sensitive
:
C1
sotorasib
Sensitive: C1 - Off-label
sotorasib
Sensitive
:
C1
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