^
    BIOMARKER:

    KRAS amplification

    i
    Other names: KRAS, KRAS1, KRAS2, Kirsten rat sarcoma viral oncogene homolog
    Entrez ID:
    3845
    Related biomarkers:
    Expression
    Mutation
    CNA
    Others
    KRAS amplification
    Melanoma
    sorafenib
    Sensitive: B - Late Trials
    KRAS amplification
    CRC
    EGFR inhibitor
    Resistant: C3 – Early Trials
    KRAS amplification
    CRC
    cetuximab
    Resistant: C3 – Early Trials
    KRAS amplification
    CRC
    panitumumab
    Resistant: C3 – Early Trials
    KRAS amplification
    Germ Cell Tumors
    MEK inhibitor
    Sensitive: C3 – Early Trials
    KRAS amplification
    NSCLC
    lorlatinib
    Resistant: C3 – Early Trials
    KRAS amplification
    Pancreatic Cancer
    binimetinib
    Resistant: D – Preclinical