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BIOMARKER:

HER-2 V777L

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Entrez ID:

Related biomarkers:

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HER-2 fusion (1)

HER-2 fusion (1)

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HER-2 V777L	HER2 Negative Breast Cancer	HER-2 V777L	HER2 Negative Breast Cancer	neratinib Sensitive: C2 – Inclusion Criteria neratinib Sensitive : C2	neratinib Sensitive: C2 – Inclusion Criteria neratinib Sensitive : C2
HER-2 V777L	Breast Cancer	HER-2 V777L	Breast Cancer	trastuzumab Resistant: C3 – Early Trials trastuzumab Resistant : C3	trastuzumab Resistant: C3 – Early Trials trastuzumab Resistant : C3
HER-2 V777L	HER2 Negative Breast Cancer	HER-2 V777L	HER2 Negative Breast Cancer	trastuzumab + neratinib Sensitive: C3 – Early Trials trastuzumab + neratinib Sensitive : C3	trastuzumab + neratinib Sensitive: C3 – Early Trials trastuzumab + neratinib Sensitive : C3
HER-2 V777L	Gastric Cancer	HER-2 V777L	Gastric Cancer	tucatinib Sensitive: D – Preclinical tucatinib Sensitive : D	tucatinib Sensitive: D – Preclinical tucatinib Sensitive : D
HER-2 V777L	Breast Cancer	HER-2 V777L	Breast Cancer	ado-trastuzumab emtansine Resistant: D – Preclinical ado-trastuzumab emtansine Resistant : D	ado-trastuzumab emtansine Resistant: D – Preclinical ado-trastuzumab emtansine Resistant : D
HER-2 V777L	Colorectal Cancer	HER-2 V777L	Colorectal Cancer	trastuzumab + tucatinib Sensitive: D – Preclinical trastuzumab + tucatinib Sensitive : D	trastuzumab + tucatinib Sensitive: D – Preclinical trastuzumab + tucatinib Sensitive : D
HER-2 V777L	Colorectal Cancer	HER-2 V777L	Colorectal Cancer	tucatinib Sensitive: D – Preclinical tucatinib Sensitive : D	tucatinib Sensitive: D – Preclinical tucatinib Sensitive : D
HER-2 V777L	Non Small Cell Lung Cancer	HER-2 V777L	Non Small Cell Lung Cancer	tucatinib Sensitive: D – Preclinical tucatinib Sensitive : D	tucatinib Sensitive: D – Preclinical tucatinib Sensitive : D
HER-2 V777L	Colorectal Cancer	HER-2 V777L	Colorectal Cancer	cetuximab Resistant: D – Preclinical cetuximab Resistant : D	cetuximab Resistant: D – Preclinical cetuximab Resistant : D
HER-2 V777L	Colorectal Cancer	HER-2 V777L	Colorectal Cancer	panitumumab Resistant: D – Preclinical panitumumab Resistant : D	panitumumab Resistant: D – Preclinical panitumumab Resistant : D