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BIOMARKER:
HER-2 S310F
i
Other names:
ERBB2, CD340, HER-2, HER2, NEU, NGL, V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
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Entrez ID:
2064
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
HER-2 amplification (129)
EGFR amplification + ERBB2 amplification (1)
EGFR exon 19 deletion + HER-2 amplification (1)
HER-2 amplification + MET amplification (1)
HER-2 amplification + PTEN deletion (1)
HER-2 exon 19 deletion (1)
MYC amplification + HER-2 amplification (1)
HER-2 amplification + CDK12 amplification (0)
YES1 amplification + HER-2 amplification (0)
HER-2 amplification (129)
EGFR amplification + ERBB2 amplification (1)
EGFR exon 19 deletion + HER-2 amplification (1)
HER-2 amplification + MET amplification (1)
HER-2 amplification + PTEN deletion (1)
HER-2 exon 19 deletion (1)
MYC amplification + HER-2 amplification (1)
HER-2 amplification + CDK12 amplification (0)
YES1 amplification + HER-2 amplification (0)
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Associations
News
Trials
VERI cancer hierarchy
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HER-2 S310F
Solid Tumor
HER-2 S310F
Solid Tumor
BDTX-189
Sensitive: C2 – Inclusion Criteria
BDTX-189
Sensitive
:
C2
BDTX-189
Sensitive: C2 – Inclusion Criteria
BDTX-189
Sensitive
:
C2
HER-2 S310F
Breast Cancer
HER-2 S310F
Breast Cancer
trastuzumab + everolimus
Sensitive: C3 – Early Trials
trastuzumab + everolimus
Sensitive
:
C3
trastuzumab + everolimus
Sensitive: C3 – Early Trials
trastuzumab + everolimus
Sensitive
:
C3
HER-2 S310F
HER2 Negative Breast Cancer
HER-2 S310F
HER2 Negative Breast Cancer
trastuzumab + neratinib
Sensitive: C3 – Early Trials
trastuzumab + neratinib
Sensitive
:
C3
trastuzumab + neratinib
Sensitive: C3 – Early Trials
trastuzumab + neratinib
Sensitive
:
C3
HER-2 S310F
Lung Adenocarcinoma
HER-2 S310F
Lung Adenocarcinoma
afatinib
Sensitive: C4 – Case Studies
afatinib
Sensitive
:
C4
afatinib
Sensitive: C4 – Case Studies
afatinib
Sensitive
:
C4
HER-2 S310F
Colorectal Cancer
HER-2 S310F
Colorectal Cancer
afatinib
Sensitive: C4 – Case Studies
afatinib
Sensitive
:
C4
afatinib
Sensitive: C4 – Case Studies
afatinib
Sensitive
:
C4
HER-2 S310F
HER2 Negative Breast Cancer
HER-2 S310F
HER2 Negative Breast Cancer
lapatinib
Sensitive: C4 – Case Studies
lapatinib
Sensitive
:
C4
lapatinib
Sensitive: C4 – Case Studies
lapatinib
Sensitive
:
C4
HER-2 S310F
Gallbladder Cancer
HER-2 S310F
Gallbladder Cancer
lapatinib
Sensitive: C4 – Case Studies
lapatinib
Sensitive
:
C4
lapatinib
Sensitive: C4 – Case Studies
lapatinib
Sensitive
:
C4
HER-2 S310F
Non Small Cell Lung Cancer
HER-2 S310F
Non Small Cell Lung Cancer
ado-trastuzumab emtansine
Sensitive: D – Preclinical
ado-trastuzumab emtansine
Sensitive
:
D
ado-trastuzumab emtansine
Sensitive: D – Preclinical
ado-trastuzumab emtansine
Sensitive
:
D
HER-2 S310F
Colorectal Cancer
HER-2 S310F
Colorectal Cancer
cetuximab
Resistant: D – Preclinical
cetuximab
Resistant
:
D
cetuximab
Resistant: D – Preclinical
cetuximab
Resistant
:
D
HER-2 S310F
Colorectal Cancer
HER-2 S310F
Colorectal Cancer
panitumumab
Resistant: D – Preclinical
panitumumab
Resistant
:
D
panitumumab
Resistant: D – Preclinical
panitumumab
Resistant
:
D
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