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BIOMARKER:

GNAQ mutation

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Other names: GNAQ, G Protein Subunit Alpha Q, Guanine Nucleotide Binding Protein (G Protein) Q Polypeptide, Guanine Nucleotide-Binding Protein G(Q) Subunit Alpha, Guanine Nucleotide-Binding Protein Alpha-Q, GAQ, Epididymis Secretory Sperm Binding Protein, G-ALPHA-Q, CMC1, SWS
Entrez ID:
Related biomarkers:
GNAQ mutation
Melanoma
selumetinib
Sensitive: C2 – Inclusion Criteria
GNAQ mutation
Uveal Melanoma
trametinib
Sensitive: C2 – Inclusion Criteria
GNAQ mutation
Melanoma
vorinostat
Sensitive: C2 – Inclusion Criteria
GNAQ mutation
Uveal Melanoma
pembrolizumab
Sensitive: C3 – Early Trials
GNAQ mutation
Uveal Melanoma
cabozantinib capsule
Sensitive: C3 – Early Trials
GNAQ mutation
Uveal Melanoma
AEB071
Sensitive: C3 – Early Trials
GNAQ mutation
RCC
nivolumab
Sensitive: C3 – Early Trials
GNAQ mutation
Melanoma
trametinib + dabrafenib
Sensitive: C3 – Early Trials
GNAQ mutation
Uveal Melanoma
AEB071 + AHT956
Sensitive: D – Preclinical
GNAQ mutation
Uveal Melanoma
Tris DBA
Sensitive: D – Preclinical
GNAQ mutation
Uveal Melanoma
FR900359
Sensitive: D – Preclinical
GNAQ mutation
Uveal Melanoma
AEB071 + CGM097
Sensitive: D – Preclinical
GNAQ mutation
Uveal Melanoma
everolimus + AEB071
Sensitive: D – Preclinical
GNAQ mutation
Uveal Melanoma
binimetinib + AEB071
Sensitive: D – Preclinical
GNAQ mutation
Uveal Melanoma
JQ-1
Sensitive: D – Preclinical
GNAQ mutation
Uveal Melanoma
PD-0325901 + AEB071
Sensitive: D – Preclinical