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BIOMARKER:
FGFR3 S249C
i
Other names:
FGFR3, ACH, CD333, CEK2, JTK4, Fibroblast growth factor receptor 3
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Entrez ID:
2261
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
PD-L1 overexpression + FGFR3 amplification (2)
ALK fusion + MYC amplification + CCND1 deletion + FGFR3 deletion (1)
ER positive + FGFR3 amplification (1)
FGFR2 underexpression + FGFR3 mutation (1)
FGFR3-TACC3 fusion + FGFR3 V555M (1)
IDH wild-type + FGFR3 S249C + TP53 V73fs (1)
TERT C228T + FGFR3 amplification + FGFR3-TACC3 fusion (1)
PD-L1 overexpression + FGFR3 amplification (2)
ALK fusion + MYC amplification + CCND1 deletion + FGFR3 deletion (1)
ER positive + FGFR3 amplification (1)
FGFR2 underexpression + FGFR3 mutation (1)
FGFR3-TACC3 fusion + FGFR3 V555M (1)
IDH wild-type + FGFR3 S249C + TP53 V73fs (1)
TERT C228T + FGFR3 amplification + FGFR3-TACC3 fusion (1)
›
Related tests:
therascreen® FGFR RGQ RT-PCR Kit (2)
therascreen® FGFR RGQ RT-PCR Kit (2)
Associations
News
Trials
VERI cancer hierarchy
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FGFR3 S249C
Urothelial Cancer
FGFR3 S249C
Urothelial Cancer
infigratinib
Sensitive: C3 – Early Trials
infigratinib
Sensitive
:
C3
infigratinib
Sensitive: C3 – Early Trials
infigratinib
Sensitive
:
C3
FGFR3 S249C
Urothelial Cancer
FGFR3 S249C
Urothelial Cancer
erdafitinib
Sensitive: C3 – Early Trials
erdafitinib
Sensitive
:
C3
erdafitinib
Sensitive: C3 – Early Trials
erdafitinib
Sensitive
:
C3
FGFR3 S249C
Urothelial Cancer
FGFR3 S249C
Urothelial Cancer
FGFR2 inhibitor
Resistant: C3 – Early Trials
FGFR2 inhibitor
Resistant
:
C3
FGFR2 inhibitor
Resistant: C3 – Early Trials
FGFR2 inhibitor
Resistant
:
C3
FGFR3 S249C
Urothelial Cancer
FGFR3 S249C
Urothelial Cancer
FGFR3 inhibitor
Resistant: C3 – Early Trials
FGFR3 inhibitor
Resistant
:
C3
FGFR3 inhibitor
Resistant: C3 – Early Trials
FGFR3 inhibitor
Resistant
:
C3
FGFR3 S249C
Urothelial Cancer
FGFR3 S249C
Urothelial Cancer
ARQ 087
Sensitive: C3 – Early Trials
ARQ 087
Sensitive
:
C3
ARQ 087
Sensitive: C3 – Early Trials
ARQ 087
Sensitive
:
C3
FGFR3 S249C
Urothelial Cancer
FGFR3 S249C
Urothelial Cancer
pazopanib
Sensitive: C4 – Case Studies
pazopanib
Sensitive
:
C4
pazopanib
Sensitive: C4 – Case Studies
pazopanib
Sensitive
:
C4
FGFR3 S249C
Lung Adenocarcinoma
FGFR3 S249C
Lung Adenocarcinoma
infigratinib
Sensitive: D – Preclinical
infigratinib
Sensitive
:
D
infigratinib
Sensitive: D – Preclinical
infigratinib
Sensitive
:
D
FGFR3 S249C
Urothelial Cancer
FGFR3 S249C
Urothelial Cancer
AZ8010
Sensitive: D – Preclinical
AZ8010
Sensitive
:
D
AZ8010
Sensitive: D – Preclinical
AZ8010
Sensitive
:
D
FGFR3 S249C
Urothelial Cancer
FGFR3 S249C
Urothelial Cancer
PD173074
Sensitive: D – Preclinical
PD173074
Sensitive
:
D
PD173074
Sensitive: D – Preclinical
PD173074
Sensitive
:
D
FGFR3 S249C
Urothelial Cancer
FGFR3 S249C
Urothelial Cancer
ABSK091
Sensitive: D – Preclinical
ABSK091
Sensitive
:
D
ABSK091
Sensitive: D – Preclinical
ABSK091
Sensitive
:
D
FGFR3 S249C
Bladder Cancer
FGFR3 S249C
Bladder Cancer
ponatinib
Sensitive: D – Preclinical
ponatinib
Sensitive
:
D
ponatinib
Sensitive: D – Preclinical
ponatinib
Sensitive
:
D
FGFR3 S249C
Bladder Cancer
FGFR3 S249C
Bladder Cancer
LY3076226
Sensitive: D – Preclinical
LY3076226
Sensitive
:
D
LY3076226
Sensitive: D – Preclinical
LY3076226
Sensitive
:
D
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