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BIOMARKER:
FGFR3 S249C
i
Other names:
FGFR3, ACH, CD333, CEK2, JTK4, Fibroblast growth factor receptor 3
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Entrez ID:
2261
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
FGFR3 mutation (23)
FGFR3 Y373C (6)
FGFR3 G370C (3)
FGFR3 R248C (3)
FGFR3 K650 (2)
FGFR3 V555M (2)
FGFR3 Y375C (2)
FANCA mutation + FGFR3 mutation (1)
FGFR3 A393E (1)
FGFR3 G380R (1)
FGFR3 G691R (1)
FGFR3 K508M (1)
FGFR3 K650E (1)
FGFR3 L496V (1)
FGFR3 S247C (1)
FGFR3 V443L (1)
FGFR3 V443M (1)
FGFR3 rearrangement (1)
FGFR3 mutation (23)
FGFR3 Y373C (6)
FGFR3 G370C (3)
FGFR3 R248C (3)
FGFR3 K650 (2)
FGFR3 V555M (2)
FGFR3 Y375C (2)
FANCA mutation + FGFR3 mutation (1)
FGFR3 A393E (1)
FGFR3 G380R (1)
FGFR3 G691R (1)
FGFR3 K508M (1)
FGFR3 K650E (1)
FGFR3 L496V (1)
FGFR3 S247C (1)
FGFR3 V443L (1)
FGFR3 V443M (1)
FGFR3 rearrangement (1)
›
Related tests:
therascreen® FGFR RGQ RT-PCR Kit (2)
therascreen® FGFR RGQ RT-PCR Kit (2)
Associations
News
Trials
VERI cancer hierarchy
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FGFR3 S249C
Urothelial Cancer
FGFR3 S249C
Urothelial Cancer
infigratinib
Sensitive: C3 – Early Trials
infigratinib
Sensitive
:
C3
infigratinib
Sensitive: C3 – Early Trials
infigratinib
Sensitive
:
C3
FGFR3 S249C
Urothelial Cancer
FGFR3 S249C
Urothelial Cancer
erdafitinib
Sensitive: C3 – Early Trials
erdafitinib
Sensitive
:
C3
erdafitinib
Sensitive: C3 – Early Trials
erdafitinib
Sensitive
:
C3
FGFR3 S249C
Urothelial Cancer
FGFR3 S249C
Urothelial Cancer
FGFR2 inhibitor
Resistant: C3 – Early Trials
FGFR2 inhibitor
Resistant
:
C3
FGFR2 inhibitor
Resistant: C3 – Early Trials
FGFR2 inhibitor
Resistant
:
C3
FGFR3 S249C
Urothelial Cancer
FGFR3 S249C
Urothelial Cancer
FGFR3 inhibitor
Resistant: C3 – Early Trials
FGFR3 inhibitor
Resistant
:
C3
FGFR3 inhibitor
Resistant: C3 – Early Trials
FGFR3 inhibitor
Resistant
:
C3
FGFR3 S249C
Urothelial Cancer
FGFR3 S249C
Urothelial Cancer
ARQ 087
Sensitive: C3 – Early Trials
ARQ 087
Sensitive
:
C3
ARQ 087
Sensitive: C3 – Early Trials
ARQ 087
Sensitive
:
C3
FGFR3 S249C
Urothelial Cancer
FGFR3 S249C
Urothelial Cancer
pazopanib
Sensitive: C4 – Case Studies
pazopanib
Sensitive
:
C4
pazopanib
Sensitive: C4 – Case Studies
pazopanib
Sensitive
:
C4
FGFR3 S249C
Lung Adenocarcinoma
FGFR3 S249C
Lung Adenocarcinoma
infigratinib
Sensitive: D – Preclinical
infigratinib
Sensitive
:
D
infigratinib
Sensitive: D – Preclinical
infigratinib
Sensitive
:
D
FGFR3 S249C
Urothelial Cancer
FGFR3 S249C
Urothelial Cancer
AZ8010
Sensitive: D – Preclinical
AZ8010
Sensitive
:
D
AZ8010
Sensitive: D – Preclinical
AZ8010
Sensitive
:
D
FGFR3 S249C
Urothelial Cancer
FGFR3 S249C
Urothelial Cancer
PD173074
Sensitive: D – Preclinical
PD173074
Sensitive
:
D
PD173074
Sensitive: D – Preclinical
PD173074
Sensitive
:
D
FGFR3 S249C
Urothelial Cancer
FGFR3 S249C
Urothelial Cancer
ABSK091
Sensitive: D – Preclinical
ABSK091
Sensitive
:
D
ABSK091
Sensitive: D – Preclinical
ABSK091
Sensitive
:
D
FGFR3 S249C
Bladder Cancer
FGFR3 S249C
Bladder Cancer
ponatinib
Sensitive: D – Preclinical
ponatinib
Sensitive
:
D
ponatinib
Sensitive: D – Preclinical
ponatinib
Sensitive
:
D
FGFR3 S249C
Bladder Cancer
FGFR3 S249C
Bladder Cancer
LY3076226
Sensitive: D – Preclinical
LY3076226
Sensitive
:
D
LY3076226
Sensitive: D – Preclinical
LY3076226
Sensitive
:
D
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